肿瘤患者血小板输注效果的影响因素分析  

Analysis of Influencing Factor of Platelet Transfusion Effect in Tumor Patients

作　　者：苏日古嘎 珠丽 马敬 Suriguga;Zhu Li;Ma Jing(Inner Mongolia Hospital,Peking University Cancer Hospital(Cancer Hospital Affiliated to Inner Mongolia Medical University),Hohhot 010020,Inner Mongolia Autonomous Region,China)

机构地区：[1]北京大学肿瘤医院内蒙古医院(内蒙古医科大学附属肿瘤医院),内蒙古自治区呼和浩特010020

出　　处：《中国社区医师》2025年第3期42-44,共3页Chinese Community Doctors

基　　金：2022年度内蒙古自治区卫生健康科技计划项目(编号:202202224)。

摘　　要：目的:分析肿瘤患者血小板输注效果的影响因素。方法:回顾性分析2021年12月—2022年12月于北京大学肿瘤医院内蒙古医院就诊的200例肿瘤患者的临床资料,根据血小板输注疗效分为血小板输注有效组(n=140)及血小板输注无效组(n=60),收集两组患者的一般资料,包括性别、年龄、文化程度、民族、输血次数、血小板来源、是否存在血小板抗体,通过Logistic多因素分析肿瘤患者血小板输注效果的影响因素。结果:输血次数>6次、全血制备血小板、存在血小板抗体是肿瘤患者血小板输注无效的独立危险因素(P<0.001)。结论:输血次数、血小板来源、存在血小板抗体会影响肿瘤患者血小板输注效果,临床对患者进行血小板输注时,应考虑上述因素,从而为患者制定个性化的治疗方案。Objective:To analyze the influencing factor of platelet transfusion effect in tumor patients.Methods:The clinical data of 200 tumor patients who were admitted to Inner Mongolia Hospital,Peking University Cancer Hospital from December 2021 to December 2022 were retrospectively analyzed.The patients were divided into effective group(n=140)and ineffective group(n=60)according to the efficacy of platelet transfusion.The general data of patients in the two groups were collected,including gender,age,education level,ethnicity,number of blood transfusions,platelet source,and presence/absence of platelet antibody.Logistic multivariate analysis was used to analyze the influencing factors of platelet transfusion effect in tumor patients.Results:The number of blood transfusions>6 times,platelet preparation from whole blood,and the presence of platelet antibodies were independent risk factors for ineffective platelet transfusion(P<0.001).Conclusion:The number of blood transfusions,platelet source,and presence of platelet antibodies affect the effect of platelet transfusion,and the above factors should be considered when patients receive platelet transfusion in clinical practice,so as to formulate personalized treatment regimens for patients.

关 键 词：肿瘤 血小板输注 血小板抗体 

分 类 号：R457.1[医药卫生—治疗学]