小儿热速清颗粒联合利巴韦林在急性上呼吸道感染患儿中的应用效果  

Application Effect of Xiaoer Resuqing Granule Combined with Ribavirin in the Children with Acute Upper Respiratory Tract Infection

作　　者：李亚贞 王荣春 LI Yazhen;WANG Rongchun(Department of Pediatrics,Danfeng County Hospital,Shangluo 726200,China)

机构地区：[1]丹凤县医院儿科,陕西商洛726200

出　　处：《反射疗法与康复医学》2024年第21期29-33,共5页Reflexology And Rehabilitation Medicine

摘　　要：目的探讨小儿热速清颗粒联合利巴韦林治疗在急性上呼吸道感染患儿中的效果。方法选取2023年5月—2024年5月丹凤县医院收治的96例急性上呼吸道感染患儿为研究对象,按随机数字表法将其分为对照组和观察组,各48例。两组入院后均行常规对症处理,对照组采用利巴韦林治疗,观察组在对照组基础上联合小儿热速清颗粒治疗,两组均治疗1个疗程。比较两组的康复情况、炎症因子水平、中医证候积分、临床疗效及不良反应发生情况。结果观察组咳嗽、流涕、鼻塞、咽痛消失时间均短于对照组,组间差异有统计学意义(P<0.05)。治疗后,观察组白细胞介素-8、白细胞介素-1、超敏C反应蛋白水平均低于对照组,组间差异有统计学意义(P<0.05);观察组发热、咳嗽、咽痛积分均低于对照组,组间差异有统计学意义(P<0.05)。观察组治疗总有效率为97.92%,高于对照组的85.42%,差异有统计学意义(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论在小儿急性上呼吸道感染中应用小儿热速清颗粒联合利巴韦林治疗,可促进患儿的症状康复,缓解炎症反应,提升临床疗效,且安全性高,值得应用。Objective To investigate the effect of Xiaoer Resuqing granule combined with ribavirin in the treatment of children with acute upper respiratory tract infection.Methods Ninety-Six children with acute upper respiratory tract infection treated in Danfeng County Hospital from May 2023 to May 2024 were selected as the research objects,and were divided into a control group and an observation group according to random number table method,with 48 cases in each group.Both groups received routine symptomatic treatment after admission,the control group was treated with ribavirin,and the observation group was treated with Xiaoer Resuqing granule on the basis of the control group,both groups received 1 course of treatment.The recovery condition,inflammatory factor level,Traditional Chinese Medicine syndrome score,clinical efficacy and occurrence of adverse reactions were compared between the two groups.Results The disappearance time of cough,runny nose,stuffy nose and sore throat in observation group were shorter than those in control group,and the differences between the groups were statistically significant(P<0.05).After treatment,the levels of interleukin-8,interleukin-1 and hypersensitive C-reactive protein in observation group were lower than those in control group,and the differences between the groups were statistical significance(P<0.05);the scores of fever,cough and sore throat in the observation group were lower than those in the control group,and the differences between the groups were statistically significant(P<0.05).The total effective rate of the observation group was 97.92%,which was higher than 85.42%of the control group,and the difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The application of Xiaoer Resuqing granule combined with ribavirin in the treatment of children with acute upper respiratory tract infection can promote the recovery of symptoms,relieve inflammation,improve clinical effic

关 键 词：小儿急性上呼吸道感染 利巴韦林 小儿热速清颗粒 炎症 

分 类 号：R725.6[医药卫生—儿科]