环泊酚联合盐酸瑞芬太尼在行无痛胃镜检查患者中的麻醉效果  

Anesthetic Effect of Cipofol Combined with Remifentanil Hydrochloride in Patients Undergoing Painless Gastroscopy

作　　者：于钰凌洁 YU Yulingjie(Department of Anesthesiology,Yunyan District People's Hospital of Guiyang City,Guiyang 553000,China)

机构地区：[1]贵阳市云岩区人民医院麻醉科,贵州贵阳553000

出　　处：《反射疗法与康复医学》2024年第21期91-94,共4页Reflexology And Rehabilitation Medicine

摘　　要：目的探讨环泊酚联合盐酸瑞芬太尼在无痛胃镜检查中的应用价值。方法选取2021年1月—2023年12月于贵阳市云岩区人民医院行无痛胃镜检查的102例患者为研究对象,按随机数字表法将其分为对照组和观察组,每组51例。对照组患者给予丙泊酚联合盐酸瑞芬太尼麻醉,观察组患者给予环泊酚联合盐酸瑞芬太尼麻醉。比较两组的麻醉效果、生命体征波动、麻醉情况、并发症发生情况。结果两组麻醉总有效率比较,差异无统计学意义(P>0.05)。麻醉诱导前时,两组生命体征波动比较,差异无统计学意义(P>0.05);进镜即刻、肠镜检查结束时,观察组心率、收缩压、舒张压均高于对照组,组间差异有统计学意义(P<0.05)。两组麻醉起效时间、苏醒时间、离室时间比较,组间差异无统计学意义(P>0.05)。观察组不良反应发生率为3.92%,低于对照组的15.69%,差异有统计学意义(P<0.05)。结论环泊酚联合盐酸瑞芬太尼应用于无痛胃镜检查中能够更有效地稳定患者生命体征,减少波动,且不良反应较少,值得广泛应用。Objective To explore the application value of ciprofol combined with remifentanil hydrochloride in painless gastroscopy.Methods A total of 102 patients who underwent painless gastroscopy in Yunyan District People's Hospital of Guiyang City from January 2021 to December 2023 were selected as the research objects,they were divided into the control group and the observation group according to the random number table method,with 51 cases in each group.Patients in the control group were given anesthesia with propofol combined with remifentanil hydrochloride,while patients in the observation group were given anesthesia with ciprofol combined with remifentanil hydrochloride.The anesthetic effects,fluctuations in vital signs,anesthesia conditions and the occurrence of complications were compared between the two groups.Results There was not statistically significant difference in the total effective rate of anesthesia between the two groups(P>0.05).Before anesthesia induction,there was not statistically significant difference in the fluctuations of vital signs between the two groups(P>0.05);immediately upon the insertion of the endoscope and at the end of the colonoscopy,the heart rate,systolic blood pressure and diastolic blood pressure in the observation group were higher than those of the control groups,and the differences between the groups were statistically significant(P<0.05).There was not statistically significant difference between the two groups in terms of the onset time of anesthesia,the recovery time and the time of leaving the examination room(P>0.05).The incidence rate of adverse reactions in the observation group was 3.92%,which was lower than 15.69%in the control group,and the difference was statistically significant(P<0.05).Conclusion The combination of ciprofol and remifentanil hydrochloride used in painless gastroscopy can stabilize patients'vital signs more effectively,reduce fluctuations,and has fewer adverse reactions.It is worthy of wide application.

关 键 词：无痛胃镜检查 环泊酚 盐酸瑞芬太尼 麻醉效果 不良反应 

分 类 号：R614[医药卫生—麻醉学]