重组人脑利钠肽联合盐酸胺碘酮治疗急性心肌梗死行急诊PCI术后新发心房颤动患者的临床疗效分析  

Analysis of the Clinical Efficacy of Recombinant Human Brain Natriuretic Peptide Combined with Amiodarone Hydrochloride in the Treatment of Patients with New-Onset Atrial Fibrillation after Emergency PCI for Acute Myocardial Infarction

作　　者：何璐 HE Lu(Department of Emergency,Guizhou Architectural Hospital,Guiyang 550000,China)

机构地区：[1]贵州省建筑医院急诊科,贵州贵阳550000

出　　处：《反射疗法与康复医学》2024年第21期147-150,共4页Reflexology And Rehabilitation Medicine

摘　　要：目的探讨重组人脑利钠肽联合盐酸胺碘酮治疗急性心肌梗死行急诊经皮冠状动脉介入术(PCI)术后新发心房颤动患者的临床疗效。方法回顾性分析2020年6月—2022年6月贵州省建筑医院收治的102例急性心肌梗死行急诊PCI术后新发心房颤动患者的病历资料,根据术后治疗方式的不同将其分为对照组和研究组,每组51例。两组患者均给予基础治疗,对照组患者给予盐酸胺碘酮治疗,研究组患者在对照组的基础上给予重组人脑利钠肽治疗,两组均持续治疗1周。比较两组的心功能指标、血流动力学指标、心房颤动转复时间、临床疗效、不良反应发生情况。结果干预后,研究组左心室射血分数高于对照组,左心房内径短于对照组,收缩压、舒张压均低于对照组,心率慢于对照组,组间差异有统计学意义(P<0.05)。研究组心房颤动转复时间为(10.62±2.64)h,短于对照组的(17.76±3.14)h,差异有统计学意义(P<0.05)。研究组治疗总有效率为98.04%,高于对照组的84.31%,差异有统计学意义(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论急性心肌梗死行急诊PCI术后新发心房颤动患者应用重组人脑利钠肽联合盐酸胺碘酮治疗,可以缩短患者心房颤动转复时间,改善其心功能,降低心房颤动复发率。Objective To explore the clinical efficacy of recombinant human brain natriuretic peptide combined with amiodarone hydrochloride in the treatment of patients with new-onset atrial fibrillation after emergency percutaneous coronary intervention(PCI)for acute myocardial infarction.Methods A retrospective analysis was conducted on the medical records of 102 patients with new-onset atrial fibrillation after emergency PCI for acute myocardial infarction who were admitted to Guizhou Construction Hospital from June 2020 to June 2022,according to different postoperative treatment methods,they were divided into a control group and a research group,with 51 cases in each group,both groups were given basic treatment.Patients in the control group were treated with amiodarone hydrochloride,and patients in the research group were treated with recombinant human brain natriuretic peptide on the basis of the control group,both groups were continuously treated for one week.The cardiac function indexes,hemodynamic indexes,atrial fibrillation conversion time,clinical efficacy,and occurrence of adverse reactions were compared between the two groups.Results After the intervention,the left ventricular ejection fraction in the research group was higher than that in the control group,the inner diameter of the left atrium was shorter than that in the control group,both the systolic blood pressure and the diastolic blood pressure were lower than those in the control group,and the heart rate was slower than that in the control group.the differences between the groups were statistically significant(P<0.05).The conversion time of atrial fibrillation in the research group was(10.62±2.64)h,which was shorter than(17.76±3.14)h in the control group,and the difference was statistically significant(P<0.05).The total effective rate of treatment in the research group was 98.04%,which was higher than 84.31%in the control group,and the difference was statistically significant(P<0.05).There was not statistically significant difference in the incidence o

关 键 词：急性心肌梗死 新发心房颤动 PCI 重组人脑利钠肽 盐酸胺碘酮 

分 类 号：R541.75[医药卫生—心血管疾病]