左室整体纵向应变在糖尿病患者早期心功能损伤中的应用价值  

Application value of left ventricular global longitudinal strain in early cardiac function impairment in diabetes mellitus patients

作　　者：毕方平 刘蕊 刘小丽 金泽宏[1] BI Fangping;LIU Rui;LIU Xiaoli;JIN Zehong(Department of Ultrasound Medicine,Loudi Central Hospital,Loudi 417000,Hunan,China)

机构地区：[1]娄底市中心医院超声医学科,湖南娄底417000

出　　处：《中国现代医生》2025年第4期28-31,共4页China Modern Doctor

基　　金：湖南省娄底市科技创新计划项目临床医疗类项目(娄科发[2022]32号)。

摘　　要：目的通过二维斑点追踪成像技术,分析左室整体纵向应变(left ventricular global longitudinal strain,LVGLS)在糖尿病早期心功能损伤中的应用价值。方法选取2023年1月至2024年1月于娄底市中心医院就诊的45例糖尿病患者为研究对象。根据糖化血红蛋白(glycosylated hemoglobin,HbA1c)水平将患者分为A组(HbA1c≤11.5%,20例)和B组(HbA1c>11.5%,25例),比较两组患者的临床资料及超声心动图参数。通过多因素线性回归分析各临床资料及超声心动图参数与LVGLS的关系。结果B组患者的体质量、LVGLS均显著低于A组,HbA1c、室间隔厚度均显著高于A组(P<0.05)。多因素线性回归分析结果显示HbA1c与LVGLS存在线性关系(β=–0.511)。结论糖尿病患者的HbA1c增高是LVGLS的独立危险因素。Objective The application value of left ventricular global longitudinal strain(LVGLS)in early cardiac function impairment in diabetes mellitus was analyzed by two-dimensional speckle tracking imaging.Methods A total of 45 patients with diabetes mellitus who were treated in Loudi Central Hospital from January 2023 to January 2024 were selected as study objects.Based on the levels of glycosylated hemoglobin(HbA1c),patients were divided into group A(HbA1c≤11.5%,20 cases)and group B(HbA1c>11.5%,25 cases).The clinical data and echocardiographic parameters of two groups were compared.The relationship between clinical data,echocardiographic parameters and LVGLS was analyzed by multifactor linear regression.Results Weight and LVGLS in group B were significantly lower than those in group A,HbA1c and interventricular septal thickness were significantly higher than those in group A(P<0.05).Multifactor linear regression analysis showed that there was a linear relationship between HbA1c and LVGLS(β=–0.511).Conclusion Increased HbA1c in diabetes mellitus patients is an independent risk factor for LVGLS.

关 键 词：糖尿病 糖化血红蛋白 二维斑点追踪成像 左室整体纵向应变 超声心动图 

分 类 号：R587.1[医药卫生—内分泌]