磁共振深度学习重建对三维肝脏加速容积采集序列图像质量和病变诊断效能的价值研究  

Study on the value of deep learning reconstruction based magnetic resonance on the image quality and lesion diagnostic efficacy of 3D LAVA sequences

作　　者：程勇 张钰 刘紫渲 王紫薇[1] 张妙其 张博 帅桃[1] Cheng Yong;Zhang Yu;Liu Zixuan;Wang Ziwei;Zhang Miaoqi;Zhang Bo;Shuai Tao(Department of Radiology,West China Hospital,Sichuan University,Chengdu 610041,China;GE Healthcare MR Research Center,Beijing 102600,China)

机构地区：[1]四川大学华西医院放射科,成都610041 [2]GE医疗磁共振研究中心,北京102600

出　　处：《中国医学装备》2025年第2期37-42,共6页China Medical Equipment

摘　　要：目的:探讨磁共振(MR)深度学习重建(DLR)在三维肝脏加速容积采集(3D LAVA)序列图像质量和病变诊断效能的应用价值。方法:回顾性分析2023年6月至2023年9月于四川大学华西医院行腹部MR增强检查的45例患者MR图像资料。对LAVA序列静脉期采用常规重建和深度学习(DL)重建,获得静脉期常规LAVA和DL-LAVA两种图像。由两名放射科医师(医师1和医师2)采用5分法分别对两种图像进行整体图像质量、图像清晰度、伪影和诊断信心主观评价。客观评价肝脏、脾脏和病变图像信噪比(SNR),以及肝脏及脾脏与脂肪、肌肉、病变的对比噪声比(CNR)。两名医师分别测量最大病变最大层面的最大径及最小径并比较常规LAVA及DL-LAVA对病变的诊断效能。采用受试者工作特性(ROC)曲线评估常规LAVA与DL-LAVA的诊断效能。结果:两名医师对常规LAVA和DL-LAVA序列图像质量主观评价的一致性为中等及以上(Kappa=0.553~0.902,P<0.001)。两名医师均得出DL-LAVA序列主观图像质量、图像清晰度、伪影、诊断信心均高于常规LAVA序列(Z_(医师1)=4.24、5.49、3.50、4.47,P<0.05;Z_(医师2)=4.15、3.12、3.77、4.26,P<0.05)。DL-LAVA图像上肝脏、脾脏、病变SNR均高于常规LAVA序列(t=-20.45、-18.58、-5.51,P<0.001);肝脏及脾脏与脂肪、肌肉、的CNR也均高于常规LAVA序列(t=-20.49、-19.94、-18.05、-16.74,P<0.001)。常规LAVA与DL-LAVA序列在最大病变的最大径和最小径测量上差异均无统计学意义(P>0.05)。医师1对于常规LAVA序列和DL-LAVA序列诊断病变的AUC分别为0.897和0.916,医师2分别为0.851和0.890。结论:DLR可以提高肝脏LAVA序列图像质量,且对病变的具有较高的诊断价值。Objective:To explore the application value of deep learning reconstruction(DLR)of magnetic resonance(MR)on the image quality and lesion diagnostic efficacy of three-dimensional liver acceleration volume acquisition(3D-LAVA)sequences.Methods:A retrospective analysis was conducted on the image data of magnetic resonance imaging(MRI)of 45 patients who underwent MR contrast-enhanced examinations on abdomen at West China Hospital of Sichuan University from June 2023 to September 2023.For the venous phase of the LAVA sequence,conventional reconstruction and DLR were performed respectively to obtain conventional LAVA images and DLR-LAVA images at the venous phase.Two radiologists conducted subjective evaluation for the overall image quality,image clarity,artifacts,and diagnostic confidence of the two groups of images by using a 5-point scale.And then,the signal-to-noise ratio(SNR)of the images of liver,spleen,and lesion,as well as the contrast-to-noise ratio(CNR)of the liver,spleen to fat,muscle,and lesions were objectively evaluated.The two radiologists measured respectively the maximum and minimum diameters of the largest layer of the largest lesion,and compared the diagnostic efficacy of conventional LAVA and DLR-LAVA for lesions.The diagnostic efficacies of conventional LAVA and DLR-LAVA were respectively assessed by using the receiver operating characteristic(ROC)curve.Results:The consistency of the two radiologists'subjective evaluations for the image quality of the conventional LAVA and DLR-LAVA sequences was moderate and above moderate,with Kappa values ranging from 0.553 to 0.902,and P<0.001.Both radiologists found that the subjective image quality,image clarity,artifacts,and diagnostic confidence of the DLR-LAVA sequence were higher than those of the conventional LAVA sequence(Z_(Physician 1)=4.24,5.49,3.50,4.47,Z_(Physician 2)=4.15,3.12,3.77,4.26,P<0.05).The SNR values of the liver,spleen,and lesions in the DLR-LAVA images were all higher than those in the conventional LAVA sequence(t=-20.45,-18.58,-5.51,P<0.

关 键 词：磁共振成像(MRI) 深度学习重建(DLR) 三维肝脏加速容积采集(3D-LAVA)序列 图像质量 

分 类 号：R445.2[医药卫生—影像医学与核医学]