慢性肾脏病患者超声心动图左室心肌做功指数与左室整体长轴应变及左室心肌质量的相关性分析  

Correlation analysis of echocardiography left ventricular myocardial work index and left ventricular global long axis strain and left ventricular muscle mass in patients with chronic kidney disease

作　　者：吴多杏 周德兴 黄含音 Wu Duoxing;Zhou Dexing;Huang Hanyin(Department of Ultrasound Medicine,The Second Affiliated Hospital of Hainan Medical University,Haikou 570100,China)

机构地区：[1]海南医科大学第二附属医院超声医学科,海口570100

出　　处：《中国医学装备》2025年第2期77-81,共5页China Medical Equipment

摘　　要：目的:分析慢性肾脏病(CKD)患者超声心动图左室心肌做功指数(Tei指数)与左室整体长轴应变(LS)及左室心肌质量(LVM)的相关性。方法:回顾性分析2021年1月至2022年12月在海南医科大学第二附属医院诊治的81例CKD患者,根据估算肾小球滤过率(eGFR)检测结果将其分为轻度CKD组(47例)和中重度CKD组(34例),并选取同期体检的30名健康志愿者作为健康对照组。3组受检者均进行超声心动图检查,比较各组左室Tei指数、左室整体长轴应变(GLS)及左室各节段LS参数、LVM变化;采用Pearson分析CKD患者左室Tei指数与GLS及左室各节段LS参数、LVM的相关性。结果:各组左室Tei指数、LVM比较,健康对照组均低于轻度CKD组和中重度CKD组,差异有统计学意义(F=18.834、137.505,P<0.05);健康对照组GLS、左心室心尖部LS、心尖段前壁LS、心尖段下壁LS、心尖段侧壁LS、中间段前壁LS、中间段下壁LS、中间段侧壁LS、基底段前壁LS、基底段下壁LS和基底段侧壁LS,均高于轻度CKD组和中重度CKD组,差异有统计学意义(F=9.723~21.788,P<0.05)。经Pearson分析,CKD患者左室Tei指数与GLS、心尖段侧壁LS、中间段前壁LS呈负相关(r=-0.233、-0.263、-0.222,P<0.05),与LVM呈正相关(r=0.462,P<0.05)。结论:CKD程度越重,左室Tei指数、LVM越高,GLS及左室各节段LS越低,CKD患者的左室Tei指数与GLS、心尖段侧壁LS、中间段前壁LS、LVM具有关联性。Objective:To analyze the correlation between left ventricular myocardial work index(Tei index)and left ventricular global long-axis strain(LS),and between that and left ventricular mass(LVM)in patients with chronic kidney disease(CKD).Methods:A total of 81 CKD patients who admitted to the Second Affiliated Hospital of Hainan Medical University from January 2021 to December 2022 were retrospectively analyzed.According to the estimated glomerular filtration rate(eGFR),they were divided into mild CKD group(47 cases),and moderate and severe CKD group(34 cases).In addition,30 healthy volunteers who underwent physical examination during the same period were selected as the healthy control group.Three groups underwent electrocardiographic(ECG)examination,and the changes of left ventricular Tei index,left ventricular GLS and LS parameter of each segment of left ventricle,and LVM among three groups were compared.Pearson analysis was used to analyze the correlations between left ventricular Tei index and GLS,and between that and LS parameters of each segment of left ventricle,and between that and LVM in CKD patients.Results:Comparative results of left ventricular Tei index and LVM among all groups indicated healthy control group<mild CKD group<moderate and severe CKD group,and the differences of them among three groups were statistically significant(F=18.834,137.505,P<0.05).The comparative results of GLS,left ventricular apex LS,anterior apical segment LS,lower apical segment LS,lateral apical segment LS,anterior median segment LS,lower median segment LS,lateral medial segment LS,anterior basal segment LS,lower basal segment LS,lateral basal segment LS among all groups indicated that healthy control group>mild CKD group>moderate and severe CKD group,and the differences of them among three groups were statistically significant(F=9.723-21.788,P<0.05).According to Pearson analysis of CKD patients,left ventricular Tei index was negatively correlated with GLS,lateral apical segment LS and anterior median segment LS(r=-0.233,-0.

关 键 词：超声心动图 慢性肾脏病 左室心肌做功指数 左室整体长轴应变 左室心肌质量 

分 类 号：R692[医药卫生—泌尿科学] R445.1[医药卫生—外科学]