基于真实世界数据的两种可吸收止血纱布临床使用评价研究  

Study on the evaluation based on real-world data for clinical use of two kinds of absorbable hemostatic gauzes

作　　者：杨燕 钱正瑛 彭志方 陈珍珠 Yang Yan;Qian Zhengying;Peng Zhifang;Chen Zhenzhu(Department of Medical Engineering,The Affiliated Wuxi People's Hospital of Nanjing Medical University(Wuxi Medical Center of Nanjing Medical University,Wuxi People's Hospital),Wuxi 214023,China)

机构地区：[1]南京医科大学附属无锡人民医院(南京医科大学无锡医学中心、无锡市人民医院)医学工程处,无锡214023

出　　处：《中国医学装备》2025年第2期121-125,共5页China Medical Equipment

摘　　要：目的:研究基于真实世界数据的两种可吸收止血纱布临床使用变化趋势及影响因素,为可吸收止血纱布精细化管理提供参考依据。方法:选取2015年1月1日至2023年12月31日期间南京医科大学附属无锡人民医院27468例手术中使用的两种品牌(A品牌和B品牌)可吸收止血纱布共34658片样本数据,其中采用A品牌止血纱布的手术12729例,止血纱布18457片,采用B品牌止血纱布手术14739例,止血纱布16201片,对比分析两种可吸收止血纱布用量及费用变化趋势,以及与不同工作量指标间的相关性。结果:B品牌可吸收止血纱布总用量逐年增高,平均每例手术费用更大用量更少,主要用于风险最高的4级手术中。A品牌的18457片和B品牌的16201片可吸收止血纱布用量均与疑难危重患者占比呈正相关(r=0.232、0.593,P<0.05),与耗占比呈正相关(r=0.334、0.491,P<0.05),B品牌相较A品牌与疑难危重患者占比及耗占比正相关性更高;两种可吸收止血纱布用量均与住院手术人数相关性不显著(P>0.05);A品牌和B品牌可吸收止血纱布用量与药占比均有显著负相关性(r=-0.538、-0.696,P<0.05)。结论:基于真实世界数据的可吸收止血纱临床使用评价,能够显现临床应用中B品牌正逐年取代A品牌,临床对于较高级别的手术更愿意使用B品牌止血纱布,可指导管理部门监管可吸收止血纱使用,但也需考量临床需求和成本效益之间的平衡,促进止血材料合理使用,保障资源有效配置。Objective:To investigate the changing trends and influencing factors of two kinds of absorbable hemostatic gauze in clinical use based on real-world data,so as to provide a reference for the refined management of absorbable hemostatic gauze.Methods:Data of surgical samples of a total of 34658 pieces of absorbable hemostatic gauzes,whose brand include brand A and brand B,in 27,468 surgeries of the Affiliated Wuxi People's Hospital of Nanjing Medical University between January 1,2015 and December 31,2023 were selected.In them,12729 surgeries used hemostatic gauzes(18,457 pieces)of brand A,and 14,739 surgeries used hemostatic gauzes(16,201 pieces)of brand B.The changing trends of the usage and cost of two kinds of absorbable hemostatic gauzes were compared and analyzed,which correlations of that with the different indicators of workload also were compared and analyzed.Results:The usage amount of absorbable hemostatic gauze of brand B increased annually,which had higher average costs per surgery but lower average usage amount per surgery.Brand B was mainly used in surgery of level-4.Both the usage amounts of brand A(18,457 pieces)and brand B(16,201 pieces)showed a positive correlation with the proportion of patients with difficult and critically ill(r=0.232,0.593,P<0.05),as well as with the proportion of medical consumables expenditure(r=0.334,0.491,P<0.05).Compared to brand A,brand B demonstrated a stronger positive correlation with the proportion of patients with difficult and critically ill,and the proportion of consumables expenditure.However,there was no significant correlation between the usage amount of each brand and the number of inpatients who received surgeries(P>0.05).The usage amount of absorbable hemostatic gauze of each brand was negative correlation with the proportion of pharmaceutical expenditure(r=-0.538,-0.696,P<0.05).Conclusion:The evaluation based on real-world data for clinical use of absorbable hemostatic gauze can reveal that brand B is gradually replacing brand A in clinical application.In c

关 键 词：可吸收止血纱布 真实世界数据 变化趋势 相关性分析 

分 类 号：R197.39[医药卫生—卫生事业管理]