间歇性禁食对多囊卵巢综合征影响的研究进展  

Research progress on the impact of intermittent fasting on PCOS

作　　者：谭周英 孙传雪 杨三三 罗利华 沈义军 熊国位 熊夏婕 杨奎娅 夏黎妮 汪小飞 TAN Zhouying;SUN Chuanxue;YANG Sansan;LUO Lihua;SHEN Yijun;XIONG Guowei;XIONG Xiajie;YANG Kuiya;XIA Lini;WANG Xiaofei(People′s Hospital of Honghuagang District,Zunyi,Guizhou 563000,China)

机构地区：[1]遵义市红花岗区人民医院内分泌科,贵州遵义563000

出　　处：《现代医药卫生》2025年第2期495-501,共7页Journal of Modern Medicine & Health

基　　金：贵州省遵义市科技计划项目(遵义市科合HZ字[2023]105号)。

摘　　要：多囊卵巢综合征(PCOS)是育龄期女性最常见的内分泌代谢紊乱性疾病,以胰岛素抵抗和高雄激素血症为主要病理生理特点,可能影响机体生殖、内分泌、代谢、心理等多个系统的健康稳态,并会增加子宫内膜癌、不孕症、2型糖尿病、肥胖、心血管疾病、抑郁症等疾病的风险,严重影响女性的身心健康。目前,尚无批准用于PCOS的特效药物,间歇性禁食被证明是改善PCOS表型的有效方法,但其机制尚不清楚。该文对间歇性禁食治疗PCOS的应用现状、可能机制、前景及不足进行了综述。Polycystic ovary syndrome(PCOS)is the most common endocrine and metabolic disorder in women of childbearing age.With insulin resistance and hyperandrogenism as the main pathophysiological characteristics,PCOS may affect the health and stability of the body's reproductive,endocrine,metabolic and psychological systems,increase the risk of endometrial cancer,infertility,type 2 diabetes,obesity,cardiovascular disease and depression,and seriously affect women's physical and mental health.At present,there is no approved specific drug for polycystic ovary syndrome.Intermittent fasting has been proven to be an effective method for improving the phenotype of polycystic ovary syndrome,but its mechanism is unclear.This article will review the current application status,possible mechanisms,prospects,and shortcomings of intermittent fasting therapy for PCOS.

关 键 词：多囊卵巢综合征 间歇性禁食 胰岛素抵抗 高雄激素血症 综述 

分 类 号：R711.75[医药卫生—妇产科学]