2010—2023年安徽省发热伴血小板减少综合征季节性特征分析  

Analysis on the seasonal characteristics of sever fever with thrombocytopenia syndrome in Anhui Province from 2010 to 2023

作　　者：耿浩翔 储娜 李明 储修杰 孙永[2] 陈晴晴 龚磊[1,2] GENG Haoxiang;CHU Na;LI Ming;CHU Xiujie;SUN Yong;CHEN Qingqing;GONG Lei(Department Epidemiology and Health Statistics,of School of Public Health,Anhui Medical University,Hefei 230032,Anhui Province,China;Anhui Provincial Center for Disease Control and Prevention)

机构地区：[1]安徽医科大学公共卫生学院流行病与卫生统计学系,安徽合肥230032 [2]安徽省疾病预防控制中心

出　　处：《热带病与寄生虫学》2024年第5期262-266,288,共6页Journal of Tropical Diseases and Parasitology

基　　金：国家疾控局公共卫生人才培养支持项目(202303);安徽省现场流行病学重点专科

摘　　要：目的 探究安徽省发热伴血小板减少综合征(severe fever with thrombocytopenia syndrome,SFTS)流行的季节性特征,为SFTS的防治提供参考依据。方法 通过中国疾病预防控制信息系统传染病监测信息系统收集整理2010—2023年安徽省SFTS的月发病数和死亡数,运用集中度法分析SFTS发病的季节性强弱,圆形分布法分析SFTS发病高峰日和流行高峰期。结果 2010—2023年安徽省累计报告SFTS病例5 715例,死亡184例,年均发病率为0.661 6/10万,病死率为3.22%。发病率最低为0.001 6/10万(2010年),最高为2.310 9/10万(2023年),整体呈上升趋势(χ^(2)_(趋势)=3 518.04,P<0.01)。集中度法显示,2010—2023年安徽省SFTS的月发病数总体集中度M值为0.538,提示具有较强的季节性。圆形分布法显示,安徽省SFTS春夏季(3—8月)的发病高峰日为6月2日,流行高峰期为4月20日—7月15日;秋冬季(9月—次年2月)的发病高峰日为10月9日,流行高峰期为9月16日—11月1日。结论 安徽省SFTS发病具有较强的季节性,呈现主、次2个高峰的“双峰”分布特征。建议在流行高峰期来临前采取有效的防控措施,减少SFTS疫情的发生。Objective To investigate the seasonal patterns of severe fever with thrombocytopenia syndrome(SFTS)in population in Anhui Province for evidence to prevent and control this infection.Methods Monthly reported cases of SFTS,including deaths in Anhui Province were collected from 2010 to 2023 through the Infectious Disease Monitoring Information System under the China Information System for Disease Control and Prevention.The concentration method was used to analyze the seasonal intensity of SFTS,and circular distribution method was used to analyze the peak days and epidemic peaks of SFTS.Results In total,5715 cases of SFTS and 184 deaths were reported in Anhui Province from 2010 to 2023.The average annual incidence was 0.6616 per 100000 population,and the case fatality rate was 3.22%.The incidence rate showed an overall upward trend(χ^(2)_(trend)=3518.04,P<0.01),with the lowest morbidity increasing from 0.0016/100000 in 2010 to the highest 2.3109/100000 in 2023.The total M-value of monthly incidence concentration of SFTS was 0.538 in Anhui Province from 2010 through 2023,which indicated strong seasonality.The circular distribution analysis demonstrated that the peak incidence date of SFTS in Anhui Province was on June 2 in spring and summer seasons(March-August),and the peak epidemiological period was between April 20 and July 15.The peak incidence date was found on October 9 in autumn and winter seasons(September-February),and the peak epidemiological period was between September 16 and November 1.Conclusion The incidence of SFTS in Anhui Province has strong seasonal characteristics,showing a double-peak distribution by primary and secondary peak.Our findings suggest that effective prevention and control measures should be taken before arrival of the peak epidemic in order to reduce the occurrence of SFTS.

关 键 词：发热伴血小板减少综合征 季节性特征 集中度法 圆形分布法 

分 类 号：R511[医药卫生—内科学] R181.3[医药卫生—临床医学]