红参中氨基酸糖苷类化学成分研究进展  

Research progress on chemical constituents of amino acid glycosides of Ginseng Radix et Rhizoma Rubra

作　　者：齐梦含 郑毅男[1] 李伟[1,2,3] QI Menghan;ZHENG Yinan;LI Wei(College of Chinese Medicinal Materials,Jilin Agricultural University,Changchun 130118,China;College of Life Sciences,Jilin Agricultural University,Changchun 130118,China;Jilin Provincial International Joint Research Center for the Development and Utilization of Authentic Medicinal Materials,Changchun 130118,China)

机构地区：[1]吉林农业大学中药材学院,吉林长春130118 [2]吉林农业大学生命科学学院,吉林长春130118 [3]吉林省道地药材开发利用国际联合研究中心,吉林长春130118

出　　处：《中草药》2024年第19期6779-6788,共10页Chinese Traditional and Herbal Drugs

基　　金：国家高层次人才特殊支持计划

摘　　要：红参Ginseng Radix et Rhizoma Rubra为人参Ginseng Radix et Rhizoma的重要炮制品,在红参的加工过程中氨基酸与还原糖发生美拉德反应,形成氨基酸糖苷类物质。研究表明氨基酸糖苷类物质为红参重要的活性成分之一。目前已从红参中提取分离出精氨酸双糖苷和精氨酸果糖苷等9种氨基酸糖苷类化学成分。通过查阅近年来国内外相关文献,并结合课题组的研究工作对氨基酸糖苷类物质在化学成分、形成机制、制备工艺和药理活性方面进行综述。为进一步探索和开发红参中新的氨基酸糖苷类活性成分提供参考,为人参的合理利用提供理论依据。Hongshen(Ginseng Radix et Rhizoma Rubra)is an important processed product of Renshen(Ginseng Radix et Rhizoma).During the processing of Ginseng Radix et Rhizoma Rubra,amino acids undergo maillard reaction with reducing sugars to form amino acid glycosides.Research has proved that amino acid glycosides are one of the important active ingredients of Ginseng Radix et Rhizoma Rubra.At present,nine kinds of amino acid glycosides have been extracted and separated from Ginseng Radix et Rhizoma Rubra,including arginyl-fructosyl-glucose and arginyl-fructose.This study reviews the chemical composition,generation mechanism,production techniques,and pharmacological activity of amino acid glycosides through investigating recent pertinent domestic and international literature in addition to our research group’s findings.It provides reference for further exploration and development of new amino acid glycoside active components in Ginseng Radix et Rhizoma Rubra,and provides theoretical support for the rational utilization of Ginseng Radix et Rhizoma.

关 键 词：人参 红参 氨基酸糖苷 人工合成 精氨酸双糖苷 精氨酸果糖苷 

分 类 号：R284.1[医药卫生—中药学]