基于Citespace和VOSviewer可视化分析沉香研究的发展态势  

Visual analysis on development trend of Aquilariae Lignum Resinatum based on CiteSpace and VOSviewer

作　　者：何国浩 杨云 曾琳[1,2] 许利嘉 魏建和[1,2] 肖培根 HE Guohao;YANG Yun;ZENG Lin;XU Lijia;WEI Jianhe;XIAO Peigen(Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine,Ministry of Education&National Engineering Laboratory for Breeding of Endangered Medicinal Materials,Institute of Medicinal Plant Development,Peking Union Medical College&Chinese Academy of Medical Sciences,Beijing 100193,China;Hainan Key Laboratory of Resources Conservation and Development of Southern Medicine&Key Laboratory of Key Laboratory of Agarwood Sustainable Utilization of State Administration of Traditional Chinese Medicine,Hainan Branch of Institute of Medicinal Plant Development,Peking Union Medical College&Chinese Academy of Medical Sciences,Haikou 570311,China)

机构地区：[1]中国医学科学院北京协和医学院药用植物研究所,中草药物质基础与资源利用教育部重点实验室/濒危药材繁育国家工程实验室,北京100193 [2]中国医学科学院北京协和医学院药用植物研究所海南分所,海南省南药资源保护与开发重点实验室/国家中医药管理局沉香可持续利用重点研究室,海南海口570311

出　　处：《中草药》2024年第20期7033-7046,共14页Chinese Traditional and Herbal Drugs

基　　金：海南省院士创新平台科研项目(YSPTZX202117)

摘　　要：目的 通过对近32年沉香相关研究的文献分析,探析沉香研究领域的相关热点与前沿。方法 以中国知网(CNKI)、Web of Science (WOS)等国内外数据库为数据源,运用Citespace对数据进行处理筛选,运用VOSviewer、Citespace、COOC等软件对文献年度发文量、机构、关键词、作者等方面进行分析,绘制可视化图谱。结果 共纳入中文文献981篇,英文文献662篇。文献数量整体呈增长趋势;研究机构主要以中国医学科学院北京协和医学院药用植物研究所、中国热带农业科学院热带生物技术研究所和中国林业科学研究院热带林业研究所等为代表;中英文关键词显示,沉香的主要研究方向为沉香倍半萜、结香技术、化学成分、药理作用等;目前沉香的研究热点主要为内生真菌、次生代谢产物、沉香四醇等。结论 沉香研究目前处于稳定发展阶段,该领域的最新进展主要集中于对其结香技术的探究、药理作用的靶点、信号通路以及基因层面的深入研究等。Objective To analyze the relevant hot spots and frontiers in the research field of Chenxiang(Aquilariae Lignum Resinatum)through literature analysis of Aquilaria sinensis related research in the past 32 years.Methods Using domestic and foreign databases such as CNKI and Web of science(WOS)as data sources,Citespace was used to process and screen the data,and VOSviewer,Citespace and COOC were used to analyze the annual number of publications,institutions,keywords,authors and other contents,and visualization maps were drawn.Results A total of 981 Chinese literatures and 662 English literatures were included,and the number of literature showed an overall increasing trend.The research institutions were mainly represented by Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences and Peking Union Medical College,Institute of Tropical Bioscience and Biotechnology of the Chinese Academy of Tropical Agricultural Sciences and Research Institute of Tropical Forestry,Chinese Academy of Forestry.Keywords in both Chinese and English showed that the main research directions of Aquilariae Lignum Resinatum were agarwood sesquiterpenes,agarwood-induction technique,chemical composition,pharmacological action,etc.At present,the research focus of Aquilariae Lignum Resinatum mainly included endophytic fungi,secondary metabolites,agarotetrol,etc.Conclusion The research of Aquilariae Lignum Resinatum is currently in a steady development stage.The latest progress in this field mainly focuses on the exploration of agarwood-induction techniques,its targets and signaling pathways of pharmacological action and the deep research at the genetic level.

关 键 词：沉香 文献计量学 结香技术 沉香倍半萜 可视化分析 

分 类 号：R282.71[医药卫生—中药学] G353.1[医药卫生—中医学]