胃食管气道反流性疾病多学科研究及进展  

Multidisciplinary research and advances in gastro-oesophageal reflux disease

作　　者：吴玮[1] 王磊[1] 陈升 李连勇[2] 王刚[1] WU Wei;WANG Lei;CHEN Sheng;LI Lianyong;WANG Gang(Dapartment of Otolaryngology,the Ninth Medical Centerof Chinses PLA General Hospital,Beijing 100101,China;Department of Gastroenterology,the Ninth Medical Centerof Chinses PLA General Hospital,Beijing 100101,China)

机构地区：[1]中国人民解放军总医院第九医学中心耳鼻喉科,北京100101 [2]中国人民解放军总医院第九医学中心消化内科,北京100101

出　　处：《山东大学耳鼻喉眼学报》2024年第6期1-14,22,共15页Journal of Otolaryngology and Ophthalmology of Shandong University

基　　金：中国人民解放军总医院第九医学中心学科助推计划(21XK0103);战略支援部队特色医学中心博士毕业生科研启动基金(21ZX11)

摘　　要：咽喉反流性疾病(laryngopharyngeal reflux disease, LPRD)是人群中的一类多发病、常见病。胃食管气道反流性疾病(gastroesophageal airway reflux disease, GARD)概念提出更有益于认识、探讨气道反流性疾病的发病机制。无论GARD还是LPRD,都是众多气道问题的源头疾病,而不是单一的咽喉疾病,其临床表现多样,诊断标准之间一致性差,治疗也存在不规范、用药单一化等问题,迫切需要多学科协作联合诊治。论文从近年来该类疾病损伤机制、诊断方法、治疗进展方面进行述评,以期推动多学科交流协作。Laryngopharyngeal reflux disease(LPRD)is a common disease with a high prevalence in the population.The concept of gastroesophageal airway reflux disease(GARD)is more beneficial for understanding and studying the pathogenesis of airway reflux disease.Both GARD and LPRD are the root diseases of many airway problems rather than a single throat disease.Due to its diverse clinical manifestations,there are still controversies regarding diagnostic criteria and treatment standards,which urgently require mul-tidisciplinary cooperation.This article provides an overview of the injury mechanisms,diagnostic methods and treatment progress of this type of disease in recent years,with the aim of promoting interdisciplinary communication and collaboration.

关 键 词：胃食管气道反流 咽喉反流 发病机制 诊断 治疗 

分 类 号：R766.5[医药卫生—耳鼻咽喉科] R573.9[医药卫生—临床医学]