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作 者:孙隽然 孙晓东[1] Sun Junran;Sun Xiaodong(Department of Ophthalmology,Shanghai General Hospital,Shanghai 200080,China)
出 处:《中华实验眼科杂志》2025年第1期9-17,共9页Chinese Journal Of Experimental Ophthalmology
摘 要:治疗-延长(T&E)方案是临床常用的抗血管内皮生长因子(VEGF)药物治疗新生血管性年龄相关性黄斑变性(nAMD)方案之一,可以在有效改善视力的同时延长治疗间隔、减少就诊次数。面对亚太地区医疗资源有限、患者治疗依从性不佳,T&E方案具有独特的优势。然而目前亚太地区临床使用抗VEGF药物缺乏规范化的治疗路径,尚缺乏关于T&E方案的指南。2021年亚太玻璃体视网膜学会专家组(APVRS)回顾并总结抗VEGF药物T&E方案临床研究,结合临床实践情况制定一组关于在亚太地区使用T&E方案治疗nAMD的共识。本文就APVRS专家组提出的最新T&E治疗方案进行解读以指导临床医师规范治疗。The treat-and-extend(T&E)protocol for treating neovascular age-related macular degeneration(nAMD)is one of the commonly used anti-vascular endothelial growth factor(VEGF)treatment strategies in clinical practice.It effectively improves vision while extending treatment intervals and reducing the number of clinic visits.In the Asia-Pacific region,where medical resources are limited and patient compliance is often poor,the T&E protocol offers unique advantages.However,there are currently no guidelines on the T&E protocol in this region,and its clinical use lacks standardized treatment pathways.In 2021,the Asia-Pacific Vitreo-Retina Society(APVRS)expert panel reviewed and summarized clinical research on the anti-VEGF T&E protocol,combining this with clinical practice to develop a set of consensus recommendations for using the T&E protocol to treat nAMD in the Asia-Pacific region.This article reviews and interprets the latest T&E treatment protocol proposed by the APVRS expert panel to guide clinicians in standardized treatment.
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