胎心定量分析联合静脉导管血流诊断重度PE伴FGR孕妇胎儿心功能异常价值  

Diagnostic value of the fetal heart quantitative analysis combined with the venous catheter blood flow for the abnormal fetal cardiac function of pregnant women with severe preeclampsia and fetal growth restriction

作　　者：杜晓[1] 李瑛琪 DU Xiao;LI Yingqi(Yuncheng Central Hospital Affiliated to Shanxi Medical University,Yuncheng,Shanxi Province,044500)

机构地区：[1]山西医科大学附属运城市中心医院,044500

出　　处：《中国计划生育学杂志》2025年第2期392-396,403,共6页Chinese Journal of Family Planning

摘　　要：目的:探究胎心定量分析(fetal HQ)联合静脉导管血流对重度子痫前期(PE)伴胎儿生长受限(FGR)孕妇胎儿心功能异常的诊断价值。方法:回顾性收集2022年1月-2024年1月本院分娩的重度PE伴FGR孕妇130例为病例组(n=130),胎儿超声检查结果正常的健康孕妇152例为对照组(n=152)。采用超声心动图检查及fetal HQ图像分析,获取舒张末期整体球形指数(GSI),以及左、右心室面积变化分数(FAC)及24个节段球形指数(SI);使用彩色多普勒超声诊断仪,测量胎儿静脉导管血流指标。结果:病例组体质指数、收缩压、及舒张压均高于对照组,GSI、左心室FAC及右心室FAC均低于对照组,且病例组左心室FAC均高于右心室,病例组左心室1~11节段的SI值高于右心室,而对照组左心室1~15、22、23及24节段的SI值高于右心室,病例组左心室1~20节段的SI值和右心室1、17、20、22节段的SI值均低于对照组(均P<0.05);但两组左心室及右心室的其余节段SI值无差异(P>0.05)。病例组胎儿静脉导管血流搏动指数、阻力指数、S/A及PLI值均高于对照组胎儿(均P<0.05)。结论:fetal HQ对重度PE伴FGR胎儿的心脏形态和功能进行评估,可为诊断胎儿心功能异常提供重要参考标准;同时,检测胎儿静脉导管血流可有效评估重度PE伴FGR孕妇胎儿心功能。结合以上两种方法,可更全面评估重度PE伴FGR孕妇胎儿的心功能异常和妊娠结果。Objective: To explore the diagnostic value of the fetal heart quantitative(HQ) analysis combined with the venous catheter blood flow for the abnormal fetal cardiac function of pregnant women with severe preeclampsia and fetal growth restriction(FGR). Methods: 130 pregnant women with severe preeclampsia and FGR who had given birth in the hospital from January 2022 to January 2024 were selected in research group retrospectively. 152 pregnant women with normal fetuses by ultrasonic examination during the same period were selected in control group. Echocardiography and fetal HQ image analysis were used to obtain the end-diastolic global sphericity index(GSI), the left and right ventricular fractions of area change(FAC) and the 24-segment sphericity index(SI) of the women in the two groups. The color Doppler ultrasound diagnostic instrument was used to measure the fetal ductus venosus blood flow indicators of the women. Results: The values of body mass index, systolic blood pressure and diastolic blood pressure of the women in the research group were significantly higher than those of the women in the control group. The values of GSI, left ventricular FAC and right ventricular FAC of the women in the research group were significantly lower than those of the women in the control group. The values of FAC and the SI of 1-11 segments of the left ventricle of the women in the research group were significantly higher than those of the right ventricle. The SI value of 1-15, 22, 23 segments of the left ventricle of the women in the control group were significantly higher than those of the right ventricle. The SI value of 1-20segments of left ventricle and the SI value of 1,17,20,22segments of right ventricle of the women in the research group were significantly lower than those of the women in the control group(all P<0.05).However,there were no significant difference in the SI values of the remaining segments of the left and the right ventricle of the women between the two groups(P>0.05).The values of pulsatility index,resist

关 键 词：重度子痫前期 胎儿生长受限 胎心定量分析 静脉导管血流 心功能异常 

分 类 号：R714.5[医药卫生—妇产科学]