参加免费孕前优生健康检查妇女梅毒血清学筛查结果分析  

Analysis of the serological screening results of syphilis among women who participated in the free pre-pregnancy health examination program in Jiangsu province

作　　者：李孟兰 吴玉璘 黄丽丽 封婕 张瑞金 周青 刘帅妹 林宁 李新艳 LI Menglan;WU Yulin;HUANG Lili;FENG Jie;ZHANG Ruijin;ZHOU Qing;LIU Shuaimei;LIN Ning;Li Xinyan(Jiangsu Health Development Research Center,NHC Key Laboratory of Contraceptives Vigilance and Fertility Surveillance,Jiangsu Provincial Medical Key Laboratory of Fertility Protection and Health Technology Assessment,Nanjing,Jiangsu Province,210036)

机构地区：[1]江苏省卫生健康发展研究中心,国家卫生健康委避孕药具警戒与生育力监测重点实验室,江苏省生育力保护与卫生技术评估重点实验室,南京210036

出　　处：《中国计划生育学杂志》2025年第2期484-488,共5页Chinese Journal of Family Planning

基　　金：江苏省卫生健康委科研项目(M2020101),江苏省卫生健康委妇幼健康科研项目(F202176);江苏省科教能力提升工程(ZDXYS202210)。

摘　　要：目的:分析参加免费孕前优生健康检查(简称孕优检查)妇女梅毒血清学筛查结果,为科学防控梅、避免梅毒母婴传播提供科学依据。方法:对2010-2019年10年间江苏省参加孕优检查妇女梅毒血清学筛查结果进行分析,比较不同社会人口学特征者的差异。结果:共546 950例育龄妇女参加了梅毒血清学筛查,总阳性率为0.30%(1644/546 950)。2010-2019年梅毒抗体阳性率呈逐渐升高的趋势(χ^(2)_(趋势)=49.12,P<0.001),不同年龄段、民族、文化程度、职业、地区梅毒抗体阳性率差异均有统计学意义(P<0.05)。随着年龄的增长或文化程度的降低,梅毒抗体阳性率均随呈上升趋势(χ^(2)_(趋势)=120.50,P<0.001;χ^(2)_(趋势)=133.20,P<0.001)。结论:应结合社会人口学特征制定个性化的孕前优生健康教育和梅毒防控措施。Objective: To investigate the serological screening results of syphilis among women who participated in the free pre-pregnancy health examination program, and to provide the scientific evidences for preventing and controlling syphilis and eliminating mother-to-child transmission of syphilis. Methods: The serological screening results of syphilis among women of childbearing age who participated in the national free pre-pregnancy health examination in Jiangsu province from 2010 to 2019 were analyzed, and the differences of which among these women with different social demographic characteristics were compared. Results: A total of 546950 women of childbearing age had participated in serological screening of syphilis in Jiangsu province, and the total positive rate of syphilis antibody was 0.3%(1644/546950). From 2010 to 2019, the positive rate of syphilis antibody of the women of childbearing age showed a gradually increasing trend(trend χ^(2)=49.12, P<0.001). There were significant differences in the positive rates of syphilis antibody among the women with different age, among the women with different nationalities, among the women with different education levels, among the women with different occupations and among the women from different regions of Jiangsu province(P<0.05). The positive rate of syphilis antibody of the women of childbearing age showed a uptrend with the increase of their age or with the decrease of their education level(trendχ^(2)=120.50,P<0.001;trendχ^(2)=133.20,P<0.001).Conclusion:The personalized pre-pregnancy health education and the syphilis prevention and control measures for the women should be formulated according to the social and demographic characteristics.

关 键 词：育龄妇女 孕前优生健康检查 梅毒抗体 

分 类 号：R169.1[医药卫生—公共卫生与预防医学] R759.1