用于气相色谱分离的金属有机框架固定相的研究进展  

Advances of Metal-Organic Framework Stationary Phases for Gas Chromatographic Separations

作　　者：金言 李文博 祝雨晨 赵斌 李磊[2] 郑丹 冯飞[2] JIN Yan;LI Wen-Bo;ZHU Yu-Chen;ZHAO Bin;LI Lei;ZHENG Dan;FENG Fei(School of Chemical and Environmental Engineering,Shanghai Institute of Technology,Shanghai 201418,China;State Key Laboratory of Transducer Technology,Shanghai Institute of Microsystem and Information Technology,Chinese Academy of Sciences,Shanghai 200050,China)

机构地区：[1]上海应用技术大学化学与环境工程学院,上海201418 [2]中国科学院上海微系统与信息技术研究所,传感技术国家重点实验室,上海200050

出　　处：《分析化学》2025年第1期1-13,共13页Chinese Journal of Analytical Chemistry

基　　金：国家科技重大专项项目(No.2018AAA0103100);上海科技行动计划医学创新研究专项项目(No.22Y11900600)资助。

摘　　要：金属有机框架(MOFs)材料是金属离子或金属簇和有机配体通过配位作用构筑而成的多孔材料,具有比表面积大、热稳定性好和孔径可调等优点,在气相色谱分离领域具有广阔的应用前景。近年来,用于气相色谱固定相的MOFs材料主要包括ZIF、MIL、UiO-66、HKUST-1和IRMOFs等。基于分子筛效应、范德华力、氢键和π-π相互作用等不同分离机制,可对MOFs固定相材料的孔径、孔道微环境、框架结构、不饱和金属位点和特殊官能团进行有针对性的设计与调控。以MOFs材料为固定相的气相色谱柱对正构烷烃及其异构体、芳香族化合物及其异构体、醇/酮/醛类及其异构体与手性化合物表现出独特的分离性能。将有机聚合物和新型纳米材料与MOFs材料进行复合,可提高MOFs固定相材料的分离性能和稳定性。因此,MOFs材料有望成为一种可应用于复杂环境气体分离的固定相材料。本文主要对近年来不同种类MOFs气相色谱固定相材料的研究进展进行了综述,讨论了其作为气相色谱固定相对混合气体的分离效果及其分离机理,并展望了其未来的发展方向。Metal-organic frameworks(MOFs)are porous materials composed of metal ions or metal clusters and organic ligands by coordination,which have the advantages of large specific surface area,good thermal stability and adjustable pore size,and have a promising application in gas chromatographic separation.In recent years,MOFs materials have been used as stationary phases for gas chromatography mainly including ZIF,MIL,UiO-66,HKUST-1,IRMOFs,etc.Based on the molecular sieve effect,van der Waals forces,hydrogen bonding andπ-πinteractions,the pore size,pore microenvironment,unsaturated metal site and special functional group of the MOFs stationary phase materials can be specifically designed and regulated.MOFs materials as stationary phases have unique separation performance for n-alkanes and their isomers,aromatic compounds and their isomers,alcohols/ketones/aldehydes and their isomers,and chiral compounds.The combination of organic polymers and novel nanomaterials with MOFs materials can improve the separation performance and stability of MOFs.Therefore,MOFs materials are expected to be the promising stationary phase that can be applied to gas separation in complex environments.In this article,the research advances of various stationary phases based on MOFs for gas chromatography in recent years were reviewed.The separation performance and separation mechanism of MOFs stationary phases for mixed gas samples were discussed,and the development trends in the future were prospected.

关 键 词：金属有机框架 气相色谱 固定相 色谱分离 评述 

分 类 号：TB383.4[一般工业技术—材料科学与工程] O652.63[理学—分析化学]