血培养不同菌群感染患者血清PCT、CRP分布特点  

Distribution Characteristics Analysis of Serum PCT and CRP of Patients with Different Bacterial Flora Infections during Blood Culture

作　　者：杨维宝 季雪兰[1] 夏方 李安久[1] YANG Weibao;JI Xuelan;XIA Fang;LI Anjiu(Medical Laboratory Department,Suqian City Zhongwu Hospital,Suqian,Jiangsu 223800)

机构地区：[1]江苏省宿迁市钟吾医院医学检验科,江苏宿迁223800

出　　处：《智慧健康》2024年第34期27-29,共3页Smart Healthcare

摘　　要：目的探究血培养不同菌群感染患者降钙素原(PCT)、C反应蛋白(CRP)分布特点。方法回顾性分析2021年1月—2023年12月在本院就诊的299例疑似发生血流感染患者的临床资料,依据血培养阳性结果将患者分为感染组(n=146)与非感染组(n=153),对比两组临床基本情况及血清PCT、CRP水平。将感染组患者分为革兰氏阳性菌(G+)亚组(n=101)与革兰氏阴性菌(G-)亚组(n=43),对比两亚组血清PCT、CRP水平变化。结果感染组血清PCT、CRP水平均高于非感染组(P<0.05)。感染菌以G-为主,占比为69.18%,G+占比为29.45%,真菌占比为1.37%。G-亚组血清PCT、CRP水平菌均显著高于G+亚组(P<0.05)。结论血培养不同菌群感染患者的血清PCT、CRP存在明显差异,可作为判断病原菌种类的重要生物学指标。Objective To explore the distribution characteristics of procalcitonin(PCT)and C-reactive protein(CRP)of patients with different bacterial flora infections during blood culture.Methods The paper reviewed and analyzed clinical data of 299 suspected patients with bloodstream infections in our hospital from January 2021 to December 2023,and divided them into infection group(n=146)and non infection group(n=153)based on positive blood culture results.Clinical basic information and serum PCT and CRP levels were compared between two groups.The infected patients were divided into Gram positive bacteria(G+)subgroup(n=101)and Gram negative bacteria(G-)subgroup(n=43),changes in serum PCT and CRP levels were compared between two subgroups.Results Serum levels of PCT and CRP in infection group were higher than non infection group(P<0.05).Main infectious bacteria were G-,accounting for 69.18%,G+accounting for 29.45%and fungi for 1.37%.Levels of PCT and CRP in the G-subgroup were significantly higher than the G+subgroup(P<0.05).Conclusion There are significant difference in serum PCT and CRP levels of patients with different bacterial flora infections during blood culture,which can serve as important biological indicators for determining type of pathogen.

关 键 词：血流感染 菌群分布 降钙素原 C反应蛋白 

分 类 号：R44[医药卫生—诊断学]