杭州市0~14岁儿童血清25-羟维生素D营养状况分析  

Analysis of serum 25-hydroxy vitamin D nutritional status in 0—14 year old children in Hangzhou

作　　者：江再菊 何世波 柳强 胡道波 杨丽红 刘慧玲 JIANG Zaiju;HE Shibo;LIU Qiang;HU Daobo;YANG Lihong;LIU Huiling(Hangzhou Dian Medical Diagnosis Center,Hangzhou,Zhejiang 310030,China)

机构地区：[1]杭州迪安医学检验中心,浙江杭州310030

出　　处：《国际检验医学杂志》2025年第4期471-474,共4页International Journal of Laboratory Medicine

摘　　要：目的分析杭州市0~14岁儿童血清25-羟维生素D[25(OH)D]水平、维生素D营养状况,为预防维生素D缺乏提供科学依据。方法选取2021年1月1日至2023年12月31日在杭州迪安医学检验中心进行检测的26225例0~14岁体检健康儿童作为研究对象。采用直接化学发光法检测25(OH)D水平,并分析比较不同性别、年龄段、季节儿童25(OH)D水平和维生素D营养状况。结果女童25(OH)D水平略高于男童,差异有统计学意义(P<0.05)。研究对象随着年龄的增长,25(OH)D水平不断下降,维生素D缺乏和维生素D不足占比逐渐上升。<3岁儿童25(OH)D水平最高,10~14岁儿童25(OH)D水平最低。10~14岁男、女童维生素D营养状况占比比较,差异有统计学意义(P<0.05)。四季中春季儿童25(OH)D水平最高、夏季儿童25(OH)D水平最低。不同季节的25(OH)D水平和维生素D营养状况占比比较,差异有统计学意义(P<0.05)。冬季维生素D缺乏、维生素D不足占比高于其他季节,差异有统计学意义(P<0.05)。结论杭州市0~14岁儿童维生素D营养状况较好,但对于儿童补充维生素D的重要性仍不可忽视,应积极宣传教育,以预防维生素D缺乏的发生。Objective To analyze the serum 25-hydroxy vitamin D[25(OH)D]levels and vitamin D nutritional status of 0—14 years old children in Hangzhou,and to provide scientific basis for the prevention of vitamin D deficiency.Methods A total of 26225 healthy children aged 0 to 14 who were tested in Hangzhou Dian Medical Diagnosis Center from January 1,2021 to December 31,2023 were selected as the study objects.The 25(OH)D levels were detected by direct chemiluminescence method,and the 25(OH)D levels and vitamin D nutritional status of children with different genders,ages and seasons were analyzed and compared.Results The level of 25(OH)D in girls was slightly higher than that in boys,and the difference was statistically significant(P<0.05).With the increase of age,the level of 25(OH)D continued to decline,and the proportion of vitamin D deficiency and vitamin D insufficiency gradually increased.The level of 25(OH)D was the highest in children<3 years old and the lowest in children 10—14 years old.There was statistical significance in the proportion of vitamin D nutritional status between boys and girls aged 10 to 14(P<0.05).In the four seasons,children′s 25(OH)D level is the highest in spring and the lowest in summer.The difference of 25(OH)D level and vitamin D nutritional status in different seasons was statistically significant(P<0.05).The proportion of vitamin D deficiency and vitamin D insufficiency in winter was higher than that in other seasons,and the difference was statistically significant(P<0.05).Conclusion The nutritional status of vitamin D in 0—14 year old children in Hangzhou is good,but the importance of vitamin D supplementation for children should not be ignored,and active publicity and education should be carried out to prevent vitamin D deficiency.

关 键 词：儿童 25-羟维生素D 营养状况 维生素D缺乏 

分 类 号：R725.6[医药卫生—儿科]