胺碘酮治疗急诊冠心病合并快速性心律失常患者的临床疗效分析  

Analysis of clinical effect of amiodarone on emergency patients with coronary heart disease complicated with tachyarrhythmia

作　　者：洪雅静 张珍 HONG Ya-jing;ZHANG Zhen(Emergency Department,The 73rd Group Military Hospital of the Chinese People's Liberation Army,Xiamen 361000,China)

机构地区：[1]中国人民解放军陆军第七十三集团军医院急诊科,361000

出　　处：《中国现代药物应用》2025年第2期74-76,共3页Chinese Journal of Modern Drug Application

摘　　要：目的 探究胺碘酮治疗急诊冠心病合并快速性心律失常患者的临床疗效。方法 64例急诊冠心病合并快速性心律失常患者作为研究对象,利用最新统计学软件生成随机序列分为对照组及观察组,各32例。对照组给予普罗帕酮治疗,观察组给予胺碘酮治疗。比较两组患者的血压及心功能指标。结果 治疗后,观察组收缩压(129.34±12.37)mm Hg(1 mm Hg=0.133 kPa)、舒张压(83.14±9.25)mm Hg均低于对照组的(138.54±12.26)、(91.24±9.02)mm Hg,有统计学意义(P<0.05)。治疗后,观察组左心室射血分数(51.36±4.05)%高于对照组的(48.26±3.87)%,左心室舒张末期内径(56.21±6.34)mm小于对照组的(60.51±6.25)mm,B型脑钠肽(546.34±102.14)pg/ml低于对照组的(621.04±122.06)pg/ml,有统计学意义(P<0.05)。结论 对于急诊接收的冠心病合并快速性心律失常患者应采取快速应对措施,在此过程中使用胺碘酮治疗能够有效改善患者的血压及心功能,值得临床推广。Objective To explore the clinical efficacy of amiodarone on emergency patients with coronary heart disease complicated with tachyarrhythmia.Methods 64 emergency patients with coronary heart disease complicated with tachyarrhythmia were selected as the study subjects and divided into control group and observation group using a randomized sequence generated by the latest statistical software,with 32 cases in each group.The control group was treated with propafenone,and the observation group was treated with amiodarone.The blood pressure and cardiac function indicators were compared between the two groups.Results After treatment,the systolic blood pressure and diastolic blood pressure were(129.34±12.37) and(83.14±9.25) mm Hg(1 mm Hg=0.133 kPa) in the observation group,which were lower than(138.54±12.26) and(91.24±9.02) mm Hg in the control group,and there was statistical significance(P<0.05).After treatment,the left ventricular ejection fraction of(51.36±4.05) % in the observation group was higher than(48.26±3.87) % in the control group,the left ventricular end-diastolic diameter of(56.21±6.34) mm was smaller than(60.51±6.25) mm in the control group,and B-type brain natriuretic peptide of(546.34±102.14) pg/ml was lower than(621.04±122.06) pg/ml in the control group;there was statistical significance(P<0.05).Conclusion Rapid response measures should be taken for emergency patients with coronary heart disease complicated with tachyarrhythmia.In this process,amiodarone treatment can effectively improve the blood pressure and cardiac function of patients with,and is worthy of clinical promotion.

关 键 词：冠心病 胺碘酮 急诊 快速性心律失常 疗效 

分 类 号：R541.7[医药卫生—心血管疾病] R541.4[医药卫生—内科学]