中药治疗脾肾气虚型糖尿病肾病的临床效果  

Clinical effect of traditional Chinese medicine on diabetic nephropathy with spleen-kidney qi deficiency syndrome

作　　者：李永焕 LI Yong-huan(Department of Traditional Chinese Medicine,Xinbin County People's Hospital,Fushun 113200,China)

机构地区：[1]辽宁省抚顺市新宾县人民医院中医科,113200

出　　处：《中国现代药物应用》2025年第2期132-135,共4页Chinese Journal of Modern Drug Application

摘　　要：目的 探究中药方案应用在脾肾气虚型糖尿病肾病患者治疗中的作用。方法 122例脾肾气虚型糖尿病肾病患者,采用随机抽签方法分为观察组和对照组,每组61例。对照组采用常规西药方案进行治疗,观察组则采用中药方案进行治疗。对比两组患者的临床疗效、不良反应发生率及肾功能指标[血肌酐(Scr)、尿素氮(BUN)、血尿酸(BUA)]。结果 (1)观察组的临床疗效优于对照组,差异有统计学意义(P<0.05)。(2)观察组的不良反应发生率4.92%低于对照组的21.31%,差异有统计学意义(P<0.05)。(3)治疗前,两组患者的Scr、BUN、BUA对比差异无统计学意义(P>0.05);治疗后,观察组的Scr(130.82±20.84)μmol/L、BUN(8.37±1.33)mmol/L、BUA(423.45±67.45)μmol/L比对照组的(144.08±22.50)μmol/L、(9.54±1.49)mmol/L、(468.31±73.13)μmol/L更低,差异有统计学意义(P<0.05)。结论 将中药方案应用在脾肾气虚型糖尿病肾病患者的治疗中不仅安全性高,而且疗效更好,可以改善患者的肾功能,值得推荐。To explore the role of traditional Chinese medicine on diabetic nephropathy patients with spleen-kidney qi deficiency syndrome.Methods 122 diabetic nephropathy patients with spleen-kidney qi deficiency syndrome were divided into an observation group and a control group by random drawing method,with 61 cases in each group.The control group was treated with Western medicine,and the observation group was treated with traditional Chinese medicine.The clinical efficacy,incidence of adverse reactions and renal function indexes[ serum creatinine(Scr),blood urea nitrogen(BUN),blood uric acid(BUA)] of the two groups were compared.Results(i) The clinical efficacy of the observation group was better than that of the control group,and the difference was statistically significant(P<0.05).(ii) The incidence of adverse reactions of 4.92% in the observation group was lower than 21.31% in the control group,and the difference was statistically significant(P<0.05).(iii) Before treatment,there was no significant difference in Scr,BUN and BUA between the two groups(P>0.05).After treatment,the observation group had Scr of(130.82±20.84) μmol/L,BUN of(8.37±1.33) mmol/L,and BUA of(423.45±67.45) μmol/L,which were lower than(144.08±22.50) μmol/L,(9.54±1.49) mmol/L,and(468.31±73.13) μmol/L in the control group,and the difference was statistically significant(P<0.05).Conclusion The application of traditional Chinese medicine in the treatment of diabetic nephropathy patients with spleenkidney qi deficiency syndrome is not only safe,but also has better efficacy,and can improve the renal function of patients,which is worth recommending.

关 键 词：中药 脾肾气虚 糖尿病肾病 疗效 不良反应 肾功能 

分 类 号：R259[医药卫生—中西医结合] R277.5[医药卫生—中医内科学]