经皮穴位电刺激干预对精神分裂症药源性便秘疗效观察  

Observation on the Efficacy of Transcutaneous Acupuncture Point Electrical Stimulation Intervention for Drug-induced Constipation in Schizophrenia

作　　者：周娟 卢惠鹏 肖珊 ZHOU juan;LU Huipeng;XIAO Shan(Department of Addiction Medicine,Zhongshan Third People's Hospital,Guangdong Zhongshan 528451;Department of Psychiatric Rehabilitation,Zhongshan Third People's Hospital,Guangdong Zhongshan 528451)

机构地区：[1]中山市第三人民医院成瘾医学科,广东中山528451 [2]中山市第三人民医院精神康复科,广东中山528451

出　　处：《深圳中西医结合杂志》2024年第24期13-16,共4页Shenzhen Journal of Integrated Traditional Chinese and Western Medicine

基　　金：中山市医学科学基金项目(2021A020651)。

摘　　要：目的:研究经皮穴位电刺激治疗精神分裂症药源性便秘的效果及安全性。方法:选择2021年7月至2022年9月期间中山市第三人民医院收治的60例患有精神分裂症并伴有药源性便秘的患者,并将其随机分为两组,各30例。对照组患者按需口服通便药物治疗。观察组患者以天枢穴、足三里穴(同侧穴位成对)行经皮电刺激治疗。采用便秘严重程度量表(CSS)在干预第1周末、2周末、4周末进行疗效评价。结果:随着治疗时间的增加,观察组患者的CSS评分均有下降,差异具有统计学意义(P<0.05);对照组患者随着治疗时间的增加虽有下降,但差异无统计学意义(P>0.05);且治疗2周、4周后观察组患者CSS评分均低于对照组,差异具有统计学意义(P<0.05)。两组患者治疗过程中未见明显不良反应。结论:经皮穴位电刺激对精神分裂症药源性便秘有一定的疗效。Objective To study the effect and safety of transcutaneous acupuncture point electrical stimulation in the treatment of drug-induced constipation in schizophrenia.Methods A total of 60 patients with schizophrenia and drug-induced constipation admitted to Third People’s Hospital of Zhongshan from July 2021 to September 2022 were selected and randomly divided into two groups,with 30 cases in each group.Patients in the control group were treated with oral laxatives as needed.Patients in the observation group received transcutaneous electrical stimulation at the Tianshu and Zusanli acupoints(paired acupoints on the same side).The constipation severity scale(CSS)was used to evaluate the efficacy at the end of the 1st,2nd,and 4th weeks of intervention.Results The CSS scores of the patients in the observation group decreased with the increase of treatment time,and the differences were statistically significant(P<0.05).However,although the CSS scores of the control group decreased with the increase of treatment time,the differences were not statistically significant(P>0.05).After 2 and 4 weeks of treatment,the CSS scores of the observation group were lower than those of the control group,and the differences were statistically significant(P<0.05).No significant adverse reactions were observed in both groups during the treatment.Conclusion Transcutaneous acupuncture point electrical stimulation has a certain efficacy on drug-induced constipation in schizophrenia.

关 键 词：药源性便秘 精神分裂症 经皮穴位电刺激 

分 类 号：R442.2[医药卫生—诊断学]