特布他林联合阿奇霉素序贯疗法治疗小儿肺炎支原体肺炎的效果  

Effect of Terbutaline Combined with Azithromycin Sequential Therapy in the Treatment of Mycoplasma Pneumoniae Pneumonia in Children

作　　者：张敏敏 ZHANG Minmin(Jinjiang City Hospital,Jinjiang 362200,China)

机构地区：[1]晋江市医院(上海市第六人民医院福建医院),福建晋江362200

出　　处：《中外医学研究》2025年第4期57-60,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:分析特布他林联合阿奇霉素序贯疗法在小儿肺炎支原体肺炎(Mycoplasma pneumoniae pneumonia,MPP)中的应用效果。方法:选择2023年1月—2024年2月晋江市医院收治的120例MPP患儿作为研究对象,采用随机数表法将患儿分为A组(n=60)与B组(n=60)。A组采用阿奇霉素序贯疗法,B组采用特布他林联合阿奇霉素序贯疗法,比较两组症状与体征消退时间、血清炎症因子水平、临床疗效及不良反应。结果:B组发热、喘憋、咳嗽、肺部啰音消退时间早于A组,差异有统计学意义(P<0.05)。治疗后,两组血清C反应蛋白、肿瘤坏死因子-α、白细胞介素-6水平较治疗前降低,且B组低于A组,差异有统计学意义(P<0.05)。B组总有效率、总显效率高于A组,差异有统计学意义(P<0.05)。两组不良反应总发生率比较,差异无统计学意义(P>0.05)。结论:特布他林联合阿奇霉素序贯疗法治疗MPP患儿的效果与安全性满意。Objective:To analyze the application effect of Terbutaline combined with Azithromycin sequential therapy in the treatment of Mycoplasma pneumoniae pneumonia(MPP)in children.Method:A total of 120 children with MPP who admitted to Jinjiang City Hospital from January 2023 to February 2024 were selected,they were randomly divided into group A(n=60)and group B(n=60).Group A was given Azithromycin sequential therapy,group B was given Terbutaline combined with Azithromycin sequential therapy,the regression time of symptoms and signs,serum inflammatory factor levels,clinical efficacy and adverse reactions were compared between two groups.Result:The disappearance times of fever,wheezing,cough and pulmonary rales in group B were earlier than those in group A,and the differences were statistically significant(P<0.05).After treatment,the levels of serum C-reactive protein,tumor necrosis factor-α and interleukin-6 in two groups were lower than those before treatment,and those in group B were lower than those in group A,the differences were statistically significant(P<0.05).The total effective rate and total effective rate of group B were higher than those of group A,and the differences were statistically significant(P<0.05).There was no significant difference in the total incidence of adverse reactions between two groups(P>0.05).Conclusion:Terbutaline combined with Azithromycin sequential therapy is effective and safe in the treatment of MPP in children.

关 键 词：肺炎支原体肺炎 阿奇霉素序贯疗法 特布他林 效果 安全性 

分 类 号：R725.6[医药卫生—儿科]