探究小剂量舒芬太尼复合罗哌卡因在妊娠期糖尿病产妇剖宫产术中的麻醉效果及对血糖的影响  

Exploring the Anaesthetic Effect of Low-dose Sufentanil Combined with Ropivacaine in Cesarean Section for Women with Gestational Diabetes Mellitus and the Effect on Blood Glucose

作　　者：王武磊 WANG Wulei(Department of Anaesthesiology,Taikang Xianlin Drum Tower Hospital,Nanjing 210000,Jiangsu,China)

机构地区：[1]泰康仙林鼓楼医院麻醉科,江苏南京210000

出　　处：《糖尿病新世界》2024年第23期37-39,44,共4页Diabetes New World

摘　　要：目的 探讨小剂量舒芬太尼(sufentanil, SF)复合罗哌卡因(ropivacaine, RP)在妊娠期糖尿病(gestational diabetes mellitus, GDM)产妇剖宫产术中的麻醉效果及对血糖水平的影响。方法 选取2020年12月-2024年8月在泰康仙林鼓楼医院分娩的60例GDM产妇,按照不同麻醉方式分为两组,每组30例。对照组接受RP单独麻醉,探究组接受小剂量SF复合RP麻醉。比较两组麻醉效果、血糖控制水平、不良反应发生率。结果 探究组麻醉起效时间短于对照组,麻醉维持时间长于对照组,差异均有统计学意义(P均<0.05)。探究组切皮时、胎儿出生时、胎盘娩出后5 min、胎盘娩出后1 h以及胎盘娩出后6 h的血糖控制水平均优于对照组,差异均有统计学意义(P均<0.05)。探究组不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论 小剂量SF复合RP在GDM产妇剖宫产术中表现出更快的麻醉起效时间、更长的麻醉维持时间以及更优的血糖控制效果,同时不良反应发生率较低。Objective To investigate the anesthetic effect of low-dose sufentanil(SF)combined with ropivacaine(RP)in cesarean section for women with gestational diabetes mellitus(GDM)and the effect on blood glucose level.Methods From December 2020 to August 2024,60 GDM parturients who gave birth in Taikang Xianlin Drum Tower Hospital were selected and grouped into two groups according to different anesthesia methods,with 30 cases in each group.The control group received RP anesthesia alone,while the study group received low-dose SF combined with RP anesthesia.The anesthetic effect,blood glucose control level and incidence of adverse reactions were compared be-tween the two groups.Results The onset time of anesthesia in the study group was shorter than that in the control group,and the duration of anesthesia was longer than that in the control group,the differences were statistically signifi-cant(both P<0.05).The blood glucose control levels at the time of skin incision,at the time of fetal birth,5 min after placental delivery,1 h after placental delivery and 6 h after placental delivery in the study group were better than those in the control group,and the differences were statistically significant(all P<0.05).The incidence of adverse reac-tions in the study group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion Low-dose SF combined with RP showed faster onset of anesthesia,longer anesthesia maintenance time,and better glycemic control in cesarean section in GDM women,as well as lower incidence of adverse effects.

关 键 词：舒芬太尼 罗哌卡因 妊娠期糖尿病 剖宫产 麻醉效果 

分 类 号：R614[医药卫生—麻醉学]