中药汤剂治疗糖尿病神经病变对患者神经传导速度的影响  

Effect of Traditional Chinese Medicine Decoction on Nerve Conduction Velocity of Diabetic Neuropathy Patients

作　　者：龚雪清 刘建辉 彭小慧 GONG Xueqing;LIU Jianhui;PENG Xiaohui(Department of Internal Medicine,Shaowu Hospital of Traditional Chinese Medicine,Shaowu 354000,Fujian,China)

机构地区：[1]福建省邵武市中医院内科,福建邵武354000

出　　处：《糖尿病新世界》2024年第23期172-175,共4页Diabetes New World

摘　　要：目的 分析中药汤剂治疗糖尿病神经病变对患者神经传导速度的影响。方法 选取2023年1-12月邵武市中医院收治的88例糖尿病周围神经病变患者,按照不同治疗方式分为观察组与对照组,各44例,对照组给予甲钴胺治疗,观察组同时给予甲钴胺与益阴消渴方治疗,对比两组临床疗效、神经传导速度与神经生长因子水平。结果 观察组治疗总有效率高于对照组,差异有统计学意义(P<0.05)。治疗后,观察组正中神经和腓总神经的感觉传导速度、运动传导速度均高于对照组,差异均有统计学意义(P均<0.05)。治疗后,观察组的脑源性神经营养因子、血管内皮生长因子水平均高于对照组,髓鞘碱性蛋白水平低于对照组,差异均有统计学意义(P均<0.05)。结论 中医治疗方式对糖尿病神经病变的改善效果明显。Objective To analyze the effect of traditional Chinese medicine decoction on nerve conduction velocity in patients with diabetic neuropathy.Methods A total of 88 patients with diabetic peripheral neuropathy admitted to Sha-owu Hospital of Traditional Chinese Medicine from January to December 2023 were selected and divided into observa-tion group and control group according to different treatment methods,44 cases in each group.The control group was treated with mecobalamin,and the observation group was treated with mecobalamin and Yiyin Xiaoke Decoction at the same time.The clinical efficacy,nerve conduction velocity and nerve growth factor levels of the two groups were com-pared.Results The total effective rate of the observation group was higher than that of the control group,and the dif-ference was statistically significant(P<0.05).After treatment,the sensory conduction velocity and motor conduction velocity of median nerve and common peroneal nerve in the observation group were higher than those in the control group,and the differences were statistically significant(all P<0.05).After treatment,the levels of brain-derived neuro-trophic factor and vascular endothelial growth factor in observation group were higher than those in control group,and myelin basic protein level was lower than that in control group,and the differences were statistically significant(all P<0.05).Conclusion The improvement effect of traditional Chinese medicine treatment on diabetic neuropathy is obvi-ous.

关 键 词：益阴消渴方 糖尿病神经病变 神经传导 

分 类 号：R259[医药卫生—中西医结合]