扳机后性交时机与妊娠结局的关系研究  

Study on the relationship between intercourse timing after trigger and pregnancy outcome

作　　者：郑柳婷 ZHENG Liu-ting(Department of Gynecology,Beihai People's Hospital,Beihai 536000,China)

机构地区：[1]北海市人民医院妇科,536000

出　　处：《中国实用医药》2025年第3期52-54,共3页China Practical Medicine

摘　　要：目的探讨注射用绒促性素(HCG)扳机后性交时机对妊娠结局的影响。方法选取187对备孕夫妇,进行监测排卵或促排卵治疗,根据性交时机不同分为1组(87对夫妇)和2组(100对夫妇)。1组于HCG注射第2天(24~36 h)性交第1次,HCG注射后36~48 h阴道超声监测有排卵,扳机48 h后即安排第2次性交。2组于HCG注射当日(12 h内)安排第1次性交,HCG注射后36~48 h阴道超声监测有排卵,扳机48 h后安排第2次性交。比较两组女性临床资料及妊娠结局。结果1组女性的年龄(30.48±4.50)岁、备孕时长(18.62±18.20)个月、扳机日主导卵泡直径(20.04±1.85)mm、子宫内膜厚度(9.22±1.70)mm与2组的(30.19±4.16)岁、(20.63±22.83)个月、(20.03±2.01)mm、(9.21±1.70)mm比较,无明显差异(P>0.05)。1组妊娠34例,妊娠率39.08%;2组妊娠24例,妊娠率22.45%。1组妊娠率高于2组(P<0.05)。结论对于临床中自然试孕的夫妇,如果医院无条件及时进行或追踪到当日激素水平,当主导卵泡直径达到≥17 mm的给予HCG,建议给药后24~36、48 h性交以提高妊娠率。Objective To explore the effect of intercourse timing on pregnancy outcome after trigger of chorionic gonadotrophin for injection(HCG).Methods 187 couples preparing for pregnancy were selected for ovulation monitoring or ovulation induction treatment,and were divided into group 1(87 couples)and group 2(100 couples)based on different timing of sexual intercourse.Group 1 had sexual intercourse for the 1st time on the second day of HCG injection(24-36 h),ovulation was detected by vaginal ultrasound 36-48 h after HCG injection,and the second sexual intercourse was arranged 48 h after trigger.Group 2 had their first sexual intercourse on the day of HCG injection(within 12 h),ovulation was detected by vaginal ultrasound 36-48 h after HCG injection,and the second sexual intercourse was arranged 48 h after trigger.The clinical date of females and pregnancy outcome of the two groups were compared.Results In group 1,the age of females was(30.48±4.50)years,the pregnancy preparation time was(18.62±18.20)months,the dominant follicle diameter on trigger day was(20.04±1.85)mm and the endometrial thickness was(9.22±1.70)mm,and those in group 2 were(30.19±4.16)years,(20.63±22.83)months,(20.03±2.01)mm and(9.21±1.70)mm;there was no significant difference in comparison(P>0.05).There were 34 case of pregnancy in group 1,and the pregnancy rate was 39.08%;there were 24 cases of pregnancy in group 2,and the pregnancy rate was 22.45%.The pregnancy rate in group 1 was higher than that in group 2(P<0.05).Conclusion For couples trying to conceive naturally in the clinic,if the hospital is not equipped to carry out or track the hormone level on that day in time,HCG should be given when the dominant follicle diameter reaches≥17 mm.It is recommended that couples have intercourses at 24-36 h and 48 h after administration to improve the pregnancy rate.

关 键 词：注射用绒促性素 扳机 性交时机 妊娠率 

分 类 号：R714.8[医药卫生—妇产科学]