中药治疗布鲁氏菌病研究进展  

Advancements in Treatment of Brucellosis with Traditional Chinese Medicine

作　　者：梁晓 李丽 徐霄龙[3,4] 白颖璐 杨玉媚 祝勇 刘清泉[1,3,4] LIANG Xiao;LI Li;XU Xiaolong;BAI Yinglu;YANG Yumei;ZHU Yong;LIU Qingquan(The Traditional Chinese Medicine College,Inner Mongolia Medical University,Hohhot Inner Mongolia 010110,China;Department of Hepatology,Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University,Beijing 100010,China;Emergency and Critical Care Center,Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University,Beijing 100010,China;Pathophysiology Laboratory,Beijing Institute of Traditional Chinese Medicine,Beijing 100010,China;The Clinical Medical College(Beijing Hospital of Traditional Chinese Medicine),Beijing University of Chinese Medicine,Beijing 100029,China;Department of Respiratory Medicine,Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University,Beijing 100010,China;Department of Pulmonary Disease,Inner Mongolia Hospital Beijing Hospital of Traditional Chinese Medicine,Bayannur Inner Mongolia 015000,China)

机构地区：[1]内蒙古医科大学中医学院,内蒙古呼和浩特010110 [2]首都医科大学附属北京中医医院肝病科,北京100010 [3]首都医科大学附属北京中医医院急诊与危重症救治中心,北京100010 [4]北京市中医药研究所病生理室,北京100010 [5]北京中医药大学临床医学院,北京中医医院,北京100029 [6]首都医科大学附属北京中医医院呼吸科,北京100010 [7]北京中医医院内蒙古医院肺病科,内蒙古巴彦淖尔015000

出　　处：《中国药物警戒》2025年第2期231-234,240,共5页Chinese Journal of Pharmacovigilance

基　　金：国家中医药多学科交叉创新团队项目(ZYYCXTD-D-202201);国家中医药管理局高水平中医药重点学科建设项目(zyyzdxk-2023001);国家自然科学基金资助项目(82474428);内蒙古自治区自然科学基金资助项目(2024MS08026);祝氏过敏煎传承博士科研工作站项目。

摘　　要：目的布鲁氏菌病是一种因感染引起的传染性人畜共患疾病,常累及多个脏腑器官,慢性期迁延难愈。为补充现代医药的不足,寻求其更加安全有效的治疗方案。方法通过对近年来中药治疗布鲁氏菌病的相关文献进行梳理归纳,基于病因辨证、伤寒六经辨证、八纲辨证、卫气营血辨证共4个辨证体系对布鲁氏菌病用药及组方进行分类探讨。结果与结论经总结布鲁氏菌病的总体治法分为急、慢性期2个阶段,用药思路涉及六经、卫气营血。根据不同辨证思路予以中药治疗,具有较好的临床效果,为今后布鲁氏菌病的中药研究和临床用药提供参考。Objective To seek safer and more effective treatment options against brucellosis,which is an infectious zoonotic disease involving multiple organs and systems.Methods Literature related to the treatment of brucellosis with Traditional Chinese Medicine(TCM)in recent years was reviewed.Based on four diagnostic systems-etiological differentiation,sixmeridian syndrome differentiation of treatise on febrile diseases,eight-line syndrome differentiation,and wei-qi-ying-xue differentiation,the medications and formula composition for brucellosis were categorized.Results and Conclusion The treatment of brucellosis is divided into acute and chronic phases,with medications involving the six-meridian syndrome differentiation and the wei-qi-ying-xue differentiation.TCM has shown good clinical effects.This study is expected to provide a reference for future research on and clinical medications for brucellosis with TCM.

关 键 词：布鲁氏菌病 中药 辨证体系 宣痹汤 小柴胡汤 

分 类 号：R961[医药卫生—药理学] R994.1[医药卫生—药学]