二维横切面上胼胝体长度与枕额径比值对胎儿胼胝体长度变短的诊断价值研究  

Research on the diagnostic value of corpus callosum length to occipitofrontal diameter proportion on two-dimensional axial plane for fetal short corpus callosum

作　　者：文桂琼[1] 曾晴 李琴[1] 柳元铭[1] WEN Gui-qiong;ZENG Qing;LI Qin;LIU Yuan-ming(Department of Ultrasound,Affiliated Hospital of Guilin Medical University,Guilin Guangxi 541001,China;Department of Ultrasound,Shenzhen Maternity and Child Healthcare Hospital,Southern Medical University,Shenzhen Guangdong 518028,China)

机构地区：[1]桂林医学院附属医院超声医学科,广西桂林541001 [2]南方医科大学深圳妇幼保健院超声科,广东深圳518028

出　　处：《中国临床医学影像杂志》2025年第2期127-130,共4页Journal of China Clinic Medical Imaging

基　　金：广西壮族自治区卫生健康委自筹经费科研课题(Z-C20230810)。

摘　　要：目的:建立二维横切面上胼胝体长度与枕额径比值的正常参考值范围,并探讨其对胼胝体长度变短的诊断价值。方法:随机选取研究时间为2020年1月—2023年12月我院行产前超声检查的正常胎儿360例(正常组);临床确诊胎儿生长受限(FGR)胎儿48例(FGR组),疑诊胼胝体长度变短并证实确为胼胝体长度短小的异常胎儿76例(异常组)。对所有胎儿进行横切面上胼胝体最大前后径测量,计算胼胝体长度与枕额径比值。建立胎儿胼胝体长度/枕额径比值的正常参考值,绘制异常组、FGR组与正常组胼胝体长度与枕额径比值的复合散点图。结果:360例正常组、76例异常组和48例FGR组孕妇年龄分别为(30.6±4.6)岁、(31.5±7.9)岁、(30.7±4.5)岁,孕妇年龄组间差异比较无统计学差异(正常组和异常组P=0.152,正常组和FGR组P=0.457,异常组和FGR组P=0.083)。异常组和正常组相比较,胼胝体长度与枕额径比值有统计学差异(P<0.05),FGR组和正常组相比,胼胝体长度与枕额径比值无统计学差异(P>0.05)。异常组、FGR组与正常组胼胝体长度与枕额径比值的复合散点图结果显示,异常组胼胝体长度与枕额径比值位于正常参考值的第5百分位数线下;FGR组和异常组在复合散点图上差异不明显。结论:二维横切面上胼胝体长度与枕额径比值对胼胝体大小评估具有参考价值,比值在整个孕周相对恒定,且该比值在FGR胎儿中亦为正常,可避免因胎儿FGR导致胼胝体实际长度低于正常胎儿而误诊为胼胝体发育不良。Objective:To establish the normal reference range of the ratio of corpus callosum length to occipitofrontal diameter on two-dimensional axial plane and explore its diagnostic value for short corpus callosum.Methods:A total of 360cases of normal fetuses(normal group)and 76 cases of fetuses with suspected short corpus callosum confirmed by prenatal/postnatal MRI(abnormal group)were selected from January 2020 to December 2023,who underwent prenatal ultrasound exami-nation using the two-dimensional transverse section method in our hospital.Additionally,48 cases of fetuses with fetal growth restriction(FGR group)were clinically diagnosed.The maximum anterior-posterior diameter of the corpus callosum on the trans-verse section was measured for all fetuses,and the ratio of corpus callosum length to occipitofrontal diameter was calculated.The normal reference values for the ratio of corpus callosum length to occipitofrontal diameter in normal fetuses were estab-lished,and composite scatter plots of the ratio of corpus callosum length to occipitofrontal diameter were created for the ab-normal group,FGR group,and normal group.Results:The maternal ages of the 360 cases in the normal group,76 cases in the abnormal group,and 48 cases in the FGR group were 30.6±4.6 years old,31.5±7.9 years old,and 30.7±4.5 years old,respectively.There was no statistically significant difference in maternal age among the three groups when compared pairwise(P=0.152 between normal group and abnormal group,P=0.457 between normal group and FGR group,P=0.083 between abnormal and FGR group).There were statistically significant differences in the ratio of corpus callosum length to occipitofrontal di-ameter in both the abnormal group and FGR group(P<0.05)when compared with the normal group.The composite scatter plots of the ratio of corpus callosum length to occipitofrontal diameter for the abnormal group,FGR group,and normal group showed that the ratio in the abnormal cases was significantly lower than the 5th percentile line of the normal cases,wh

关 键 词：胎儿发育 胼胝体 超声检查 多普勒 彩色 

分 类 号：R714.431[医药卫生—妇产科学] R445.1[医药卫生—临床医学]