诊治复发性多软骨炎一例报告  

Diagnosis and treatment of recurrent polychondritis:a case report

作　　者：王静 陈文婷 郑磊 冉杰 毛青 刘慧敏 Wang Jing;Chen Wenting;Zheng Lei;Ran jie;Mao Qing;Liu Huimin(Institute of Infectious Diseases,Southwest Hospital of Army Medical University,Chongqing Key Laboratory of Infectious Disease Research,Chongqing 400038,China;Department of Nuclear Medicine,First Affiliated Hospital of Army Medical University,Chongqing 400038,China;Department of Information,First Affiliated Hospital of Army Medical University,Chongqing 400038,China)

机构地区：[1]陆军军医大学西南医院全军感染病研究所,重庆市感染病研究重点实验室,重庆400038 [2]陆军军医大学第一附属医院核医学科,重庆400038 [3]陆军军医大学第一附属医院信息科,重庆400038

出　　处：《遵义医科大学学报》2025年第2期188-192,共5页Journal of Zunyi Medical University

基　　金：陆军军医大学“战团”建设项目(NO:4175ZA383)。

摘　　要：目的报道1例罕见的复发性多软骨炎(RP)病例,分享诊治经验,提高临床医生对该病的了解,减少误诊和漏诊。方法本病主要累及鼻、耳等软骨结构和富含蛋白多糖的组织,无特异性的诊断指标,通常基于寻找临床证据和排除鉴别。然而,对于本例的中年女性患者,我们按发热待查的诊疗思路,应用PET/CT结合多学科会诊意见早期定位RP诊断。结果经激素加甲氨蝶呤的联合方案治疗,症状得以控制,病情好转出院,后期随访1年余仍未复发。结论本病例报告强调了PET/CT诊断和多学科诊疗的重要性。此外,早期发现和控制感染等并发症,为后期免疫治疗奠定了基础,联合方案可有效防止复发。Objective To report a rare case of relapsing polychondritis(RP),share the experience in diagnosis and treatment,improve clinicians’understanding of this disease,so as to reduce misdiagnosis and missed diagnosis.Methods The disease mainly affects cartilage structures such as the nose and ears and proteoglycan-rich tissues,and there are no specific diagnostic indicators,usually based on the search for clinical evidence and exclusion of differentiation.However,for the middle-aged female patient in this case,we followed the diagnosis and treatment idea of fever,and used PET/CT combined with multidisciplinary consultation to locate the diagnosis of RP.Results After treatment with the combined regimen of hormones and methotrexate,the symptoms were controlled,the patient’s condition was improved and she was discharged from the hospital.During the follow-up for more than one year,there was no recurrence.Conclusion This case report emphasizes the importance of PET/CT diagnosis and multidisciplinary diagnosis and treatment.In addition,the early detection and control of complications such as infections have laid the foundation for the subsequent immunotherapy,and the combined regimen can prevent recurrence.

关 键 词：多软骨炎 复发性 自身免疫性疾病 肺部感染 

分 类 号：R681.3[医药卫生—骨科学]