炎琥宁辅助布地奈德混悬液及α-干扰素治疗小儿支气管肺炎的临床疗效及炎症因子观察  

Clinical effect of Yanhuning assisted budesonide suspension and alpha interferon in the treatment of bronchopneumonia in children and observation of inflammatory factors

作　　者：朱敏 付才华 兰涛 Zhu Min;Fu Cai-hua;Lan tao(Department of Pediatrics,Shanggao Traditional Chinese Medicine Hospital,Yichun 336400,Jiangxi,China)

机构地区：[1]上高县中医院儿科,江西宜春336400

出　　处：《四川生理科学杂志》2025年第2期439-441,共3页

摘　　要：目的:观察炎琥宁辅助布地奈德混悬液及α-干扰素治疗小儿支气管肺炎的临床疗效及炎症因子改善情况。方法:选取2021年6月至2023年6月前来上高县中医院儿科诊治的支气管肺炎患儿68例,按照随机数表法分为对照组34例和观察组34例。对照组的患儿予以布地奈德悬混液及α-干扰素治疗,观察组患儿额外给予炎琥宁辅助治疗,两组均持续治疗7 d。比较患儿治疗效果及治疗前、7 d后炎性因子C反应蛋白(C-reactive protein,CRP)、白细胞(White Blood Cell,WBC)、降钙素原(Procalcitonin,PCT)水平及两组患儿不良反应例数。结果:观察组治疗总有效率高于对照组(P<0.05);治疗后观察组患儿CPR、WBC、PCT指标均小于对照组(P<0.05);对照组患儿不良反应例数略高于观察组,但组间比较无明显差异(P>0.05)。结论:炎琥宁联合布地奈德悬混液及α-干扰素治疗小儿支气管肺炎疗效较好,能降低患儿炎症因子水平,且不良反应风险低。Objective:To observe the clinical effect of Yanhuning assisted budesonide suspension and alpha interferon in the treatment of bronchopneumonia in children,and the improvement in inflammatory factors.Methods:Sixty-eight children with bronchopneumonia diagnosed and treated in the Shanggao County Traditional Chinese Medicine Hospital Pediatrics from June 2021 to June 2023 were selected,and divided into a control group(34 cases)and an observation group(34 cases)using a random number table.The former was treated with budesonide suspension and alpha interferon.On this basis,the latter was given adjuvant therapy with Yanhuning.Both groups underwent 7 days of continuous treatment.The two groups were compared in terms of therapeutic effects,the levels of inflammatory factors C-reactive protein(CRP),white blood cells(WBC)and procalcitonin(PCT)before treatment and after 7 days of treatment,and adverse reactions.Results:Compared with the control group,the total effective rate of the observation group was higher(P<0.05).After treatment,the levels of CRP,WBC and PCT in the observation group were lower(P<0.05).There were slightly more children with adverse reactions in the control group than in the observation group(P>0.05).Conclusion:Yanhuning combined with budesonide suspension and alpha interferon can achieve good therapeutic effect on bronchopneumonia in children.The combined treatment can lower the levels of inflammatory factors,and reduce the risk of adverse reactions in children.

关 键 词：支气管肺炎 炎琥宁 布地奈德悬混液 Α-干扰素 炎症因子 

分 类 号：R72[医药卫生—儿科]