表皮生长因子对蛋鸡生产性能、蛋品质及空肠生长发育的影响  

Effects of epidermal growth factor on production performance,egg quality,and jejunum growth and development of laying hens

作　　者：沈爽 兰忠岐 吕翔宇 王家乡[1] 李鹏[1] SHEN Shuang;LAN Zhongqi;Lü Xiangyu;WANG Jiaxiang;LI Peng

机构地区：[1]长江大学动物科学技术学院,湖北荆州434000

出　　处：《饲料研究》2025年第1期67-72,共6页Feed Research

基　　金：湖北省重大攻关项目(项目编号:2023BAA029);湖北省科技重大专项(项目编号:2020ABA016);现代农业产业技术体系建设专项(项目编号:CRAS-40-s15)。

摘　　要：试验旨在研究表皮生长因子(EGF)对蛋鸡生产性能、蛋品质及空肠生长发育的影响。选取240只260日龄体重相近(约1.25 kg)、产蛋率相近(约80%)的白来航蛋鸡,随机分为4组,每组5个重复,每个重复12只鸡。对照组饲喂基础饲粮,试验A组、B组、C组分别在基础饲粮中添加200、400和800 mg/kg EGF。预试期7 d,正式试验期42 d。结果显示,与对照组相比,试验A组、B组、C组蛋鸡平均蛋重、蛋壳强度和蛋白高度显著提高(P<0.05);试验C组的料蛋比显著降低(P<0.05),产蛋率和哈氏单位显著升高(P<0.05)。与对照组相比,试验B组、C组蛋鸡空肠的绒毛高度和绒毛宽度显著升高(P<0.05);试验B组蛋鸡空肠上皮细胞中B细胞淋巴瘤-2 (Bcl-2)蛋白表达水平显著升高(P<0.05),半胱天冬酶-3 (Caspase-3)蛋白表达水平显著降低(P<0.05)。研究表明,饲粮中添加EGF能够提高蛋鸡的生产性能,改善蛋品质,对空肠形态结构及凋亡蛋白有一定影响,其中400 mg/kg EGF组综合效果最好。The experiment aimed to study the effects of epidermal growth factor(EGF) on the production performance,egg quality,and jejunum growth and development of laying hens.A total of 240 White Leghorn laying hens,aged 260 days with similar body weight(about 1.25 kg) and similar egg production rate(about 80%),were randomly divided into four groups,each with five replicates,and each replicate consisting of 12 hens.The control group was fed a basal diet,while groups A,B,and C were fed basal diets supplemented with 200,400,and 800 mg/kg EGF,respectively.The pre-test period was seven days,and the formal test period was 42 days.The results showed that compared to the control group,the average egg weight,eggshell strength,and albumen height of hens in groups A,B,and C were significantly increased(P<0.05).The feed-to-egg ratio in group C was significantly decreased(P<0.05),while the egg production rate and Haugh unit were significantly increased(P<0.05).Compared to the control group,the villus height and width of the jejunum of hens in groups B and C were significantly increased(P<0.05),the expression level of B-cell lymphoma-2(Bcl-2) protein in the jejunum epithelial cells of hens in group B was significantly increased(P<0.05),while the expression level of cysteine aspartyl protease-3(Caspase-3) protein was significantly decreased(P<0.05).The study indicates that the addition of EGF to the diet can improve the production performance of laying hens,enhance egg quality,and have certain effects on the morphological structure of the jejunum and apoptosis-related proteins,among which 400 mg/kg EGF group has the best comprehensive effect.

关 键 词：表皮生长因子 蛋鸡 生产性能 蛋品质 空肠 

分 类 号：S831[农业科学—畜牧学]