153例老年肺结节中医证候要素特点与证型分布初探  

Studyon TCM Syndrome Elements and Distribution Syndrome Types of Pulmonary Nodules in The Elderly

作　　者：阿依达娜·毛兰 李玥 任哓玲 王林枫 雷泽杭 胡越 刘瑞[2] 花宝金[2] Ayidana·Maolan;LI Yue;REN Xiaoling;WANG Linfeng;LEI Zehang;HU Yue;LIU Rui;HUA Baojin(Beijing University of Chinese Medicine,Beijing 100029,China;Department of Oncology,Guang′anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100053,China)

机构地区：[1]北京中医药大学研究生院,北京100029 [2]中国中医科学院广安门医院肿瘤科,北京100053

出　　处：《辽宁中医杂志》2025年第2期5-9,共5页Liaoning Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金项目(82274609,82074338,82174465);国家中医药管理局中医药创新团队人才支持计划项目(ZYYCXTD-C-202205);国家中医药管理局岐黄学者支持项目;中国中医科学院优秀青年科技人才(创新类)培养专项(ZZ12-YQ-023)。

摘　　要：目的初步探索老年肺结节中医证型分布规律,为中医治疗老年肺结节提供参考依据。方法采用横断面研究方法,收集整理153例老年肺结节患者一般情况、中医四诊信息,运用因子分析、聚类分析方法对老年肺结节患者的中医证候特点和分布规律进行分析。结果老年肺结节患者中医症状以虚为主,性情急躁、乏力、疲倦、咽干、气短是该病的主要证候条目,通过因子分析提取8个公因子,结合中医证素辨证分析结果结合诊断标准、专业知识和临床实际情况归为3种证型,分别为肝郁脾肾虚兼痰证62例(40.5%)、肺脾气虚兼痰证52例(35.0%)、肝郁脾虚证39例(25.5%)。肺结节进展以肝郁脾肾虚兼痰证居多。结论老年肺结节基本中医证型为肝郁脾肾虚兼痰证、肺脾气虚兼痰证、肝郁脾虚证,复合证型及兼证可较全面准确地反映老年患者疾病状态。Objective To explore the distributionof traditional Chinese medicine syndrome types in the elderly patients with pulmonary nodules for the first time,providing reference for the treatment of pulmonary nodules in the elderlywith traditional Chinese medicine(TCM).Methods A cross-sectional study method was used to collect and sort out the information of the general conditions and the TCM four diagnostic methods of 153 elderly patients with pulmonary nodules,and descriptive statistics were performed.Factor analysis and cluster analysis methods were used to analyze the characteristics and distributionof TCM syndromes of pulmonary nodules in elderly.Results The TCM symptoms of the elderly patients with pulmonary nodules were mainly deficiency,with impatience,fatigue,tiredness,dry throatand shortness of breath being the main syndrome items of this disease.Totally 8 common factors were extracted by factor analysis,and combined with the results of TCM syndrome differentiation,professional knowledge and clinical practice,the syndromes were classified into 3types,including 62 cases(40.5%)of livers stagnation and spleen-kidney deficiency with phlegm syndrome,52 cases(35.0%)of lung-spleen Qi deficiency with phlegm syndrome and 39 cases(25.5%)of liver stagnation and spleen deficiency syndrome.Pulmonary nodule progression was mostly characterized by liver stagnation and spleen-kidney deficiency with phlegm syndrome.Conclusion The basic TCM syndrome of pulmonary nodules are liver stagnation and spleen-kidney deficiency with phlegm,lung-spleen Qi deficiency with phlegm,liver stagnation and spleen deficiency in the elderly.Composite syndrome types and comorbidities can comprehensively and accurately reflect the disease status of the elderly patients.

关 键 词：老年人 肺结节 因子分析 聚类分析 中医证型 

分 类 号：R256.1[医药卫生—中医内科学]