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作 者:黄艳霞 陈克芳[1] 梁俊雄[1] 曹林辉[1] HUANG Yanxia
机构地区:[1]中山大学孙逸仙纪念医院,广东广州510120
出 处:《中医临床研究》2025年第1期51-55,共5页Clinical Journal Of Chinese Medicine
基 金:广东省基础与应用基础研究基金项目(2019A1515111105)。
摘 要:胸腺瘤是一类进展缓慢的恶性肿瘤,归属胸腺上皮肿瘤。早期治疗首选手术完全切除,术后辅以放化疗,但复发转移率高。晚期治疗以放化疗为主,配合免疫、靶向药物等治疗。梁俊雄教授根据自己临证30余年的经验总结,认为胸腺瘤是一种以本虚标实为特征的疾病,其虚为正气亏虚,其实为痰饮、瘀血等瘀毒内陷,关键病机为正气亏虚致痰饮、瘀血等结于胸胁,瘀毒内陷而致病。其病位在胸腺,但与肝、脾、肾功能失常密切相关。基于对胸腺瘤的病机认识,梁教授提出治疗胸腺瘤时当注重补托法贯穿疾病治疗的始终,并以托里消毒散为基本方进行加减,以达益气扶正、托毒外出之目的。梁教授认为,使用补托法治疗胸腺瘤一则可扶助患者正气,二则可使邪有出路,因此应用补托法治疗胸腺瘤,每获良效,不仅可改善患者的临床症状,提高他们的生活质量,而且为进行手术或接受进一步的放化疗或免疫靶向等治疗提供有利条件。梁教授诊治胸腺瘤的临床经验可为胸腺瘤或其他恶性肿瘤提供有效的诊疗思路,值得临床同道学习。Thymoma,a malignant epithelial tumor of the thymus,typically progresses slowly.Early-stage treatment prioritizes surgical excision,complemented by postoperative radiotherapy and chemotherapy,yet faces challenges with high rates of recurrence and metastasis.Advanced stages are managed primarily through radiotherapy and chemotherapy,enhanced by immunotherapy and targeted medications.Drawing from over three decades of clinical practice,Professor LIANG Junxiong perceives thymoma as an illness marked by both deficiency and excess.The deficiency stems from a lack of Qi(气)and blood,while the excess is attributed to internal accumulation of phlegm,blood stasis,and toxins.The central pathophysiological issue is identified as Qi and blood deficiency,which results in the buildup of phlegm and blood stasis in the chest and hypochondria,leading to disease due to the entrapment of toxins.The disease is located in the thymus,but it is closely related to the dysfunction of liver,spleen,and kidney organs.Professor LIANG advocates that the tonification and expulsing toxin therapy should be emphasized throughout the treatment of thymoma,utilizing Tuoli Xiaodu San(托里消毒散)as a foundation for invigorating Qi,bolstering healthy Qi,and facilitating the expulsion of toxins.This method is believed to bolster patients’healthy Qi and provide a pathway for the elimination of pathogenic factors.The application of this approach has yielded positive outcomes,ameliorating clinical symptoms,improving patients’quality of life,and creating favorable conditions for surgical intervention or further treatments such as radiotherapy,chemotherapy,immunotherapy,and targeted therapies for thymoma patients.Professor LIANG’s expertise in treating thymoma offers valuable insights for clinicians,potentially enriching the therapeutic strategies for thymoma and other malignancies.
分 类 号:R273[医药卫生—中西医结合]
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