阴虚风动型脑梗死合并2型糖尿病危险因素分析及探讨  

An analysis and discussion on risk factors of Yin deficiency and stirring wind type cerebral infarction with type 2 diabetes mellitus

作　　者：刘安婷 霍晨露 李双 朱艳[2] LIU Anting

机构地区：[1]安徽中医药大学,安徽合肥230038 [2]安徽中医药大学第二附属医院,安徽合肥230061

出　　处：《中医临床研究》2025年第1期116-120,共5页Clinical Journal Of Chinese Medicine

基　　金：卫生健康杰出人才项目[(2022)392号];安徽省临床医学研究中心[安徽省科技厅皖科社秘(2023)83号];高校优秀中青年骨干人才国内外访学研修项目(gxgnfx2021122);2023年度省级临床重点专科建设项目[皖卫函(2023)320号]。

摘　　要：目的:探索阴虚风动型脑梗死合并2型糖尿病(Type 2 Diabetes Mellitus,T2DM)的高危因素。方法:采用回顾性调查的方法,收集2023年1月-12月于安徽中医药大学第二附属医院老年病一科就诊的145例脑梗死合并T2DM患者的一般资料及实验室指标,按中医辨证分为阴虚风动型脑梗死合并T2DM组70例、非阴虚风动型脑梗死合并T2DM组75例。采用二元Logistic回归分析及受试者工作特征曲线(Receiver Operating Characteristic Curve,ROC)探索其危险因素及预测性指标。结果:阴虚风动型脑梗死合并T2DM组的年龄、D–二聚体、超敏C反应蛋白(high sensitivity C–reactive Protein,hs–CRP)与非阴虚风动型脑梗死合并T2DM组存在显著差异(P<0.05);二元Logistic回归分析结果显示:年龄、D–二聚体是阴虚风动型脑梗死合并T2DM发病的危险因素(OR>1,P<0.05);ROC分析表明,年龄和D–二聚体对阴虚风动型脑梗死合并T2DM发生的预测性能较好。结论:阴虚风动型脑梗死合并T2DM的危险因素与其他证型间存在差异;年龄增长、D–二聚体升高可导致阴虚风动型脑梗死合并T2DM发病的风险增加。Objective:To explore the risk factors of Yin(阴)deficiency and stirring wind type cerebral infarction with type 2 diabetes mellitus(T2DM).Methods:A retrospective survey was conducted to collect the general data and laboratory indicators of 145 patients with cerebral infarction complicated with T2DM who were admitted to the Department of Geriatrics of the Second Affiliated Hospital of Anhui University of Chinese Medicine from January 2023 to December 2023.There were 70 cases in the Yin deficiency and stirring wind type cerebral infarction combined with T2DM group,and 75 cases in the non-Yin deficiency and stirring wind type cerebral infarction combined with T2DM group.Binary logistic regression analysis and ROC were used to explore the risk factors and predictive indicators.Results:The age and D-dimer in the Yin deficiency and stirring wind type cerebral infarction combined with T2DM group were significantly higher than those in the non-Yin deficiency and stirring wind type cerebral infarction with T2DM group(P<0.05).The results of binary logistic regression analysis showed that age,D-dimer and hs-CRP were risk factors for the incidence of Yin deficiency and stirring wind type cerebral infarction complicated with T2DM(OR>1,P<0.05).ROC analysis showed that age and D-dimer had better predictive performance in the occurrence of Yin deficiency and stirring wind type cerebral infarction complicated with T2DM.Conclusion:There are differences between the risk factors of Yin deficiency and stirring wind type cerebral infarction complicated with T2DM and other syndrome types,and the risk of Yin deficiency and stirring wind type cerebral infarction complicated with T2DM increases with older age and higher D-dimer.

关 键 词：阴虚风动型脑梗死 2型糖尿病 危险因素 预测指标 

分 类 号：R587.1[医药卫生—内分泌]