电针神庭、百会穴对老年患者腹腔镜胆囊切除术后早期认知功能的影响  

Influence of electroacupuncture at Shenting and Baihui acupoints on early cognitive function of elderly patients after laparoscopic cholecystectomy

作　　者：郑颖[1] 曾妍 张孟昕[1] ZHENG Ying;ZENG Yan;ZHANG Meng-xin(Department of Anesthesiology,Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine,Fuzhou 350000,China)

机构地区：[1]福建中医药大学附属人民医院麻醉科,350000

出　　处：《中国现代药物应用》2025年第3期7-10,共4页Chinese Journal of Modern Drug Application

基　　金：福建中医药大学校管课题临床专项资助(项目编号:XB2022113)。

摘　　要：目的探究电针神庭、百会穴对老年患者腹腔镜胆囊切除术后早期认知功能的影响。方法选取64例老年腹腔镜胆囊切除术患者,根据随机数字表法分为对照组和观察组,每组32例。两组患者均行常规麻醉诱导,对照组进行常规静吸复合全身麻醉,观察组在静吸复合全身麻醉的基础上电针刺激神庭、百会穴。比较两组患者术后早期认知功能障碍发生率以及各时间点的简易智力状态检查量表(MMSE)评分、蒙特利尔认知评估量表(MoCA)评分,术前、术毕认知功能相关血液指标[脑源性神经营养因子(BDNF)、中枢神经特异蛋白(S100-β)]。结果观察组术后3 h、1 d、3 d认知功能障碍发生率分别为34.4%、18.8%、6.3%,均低于对照组的59.4%、43.8%、25.0%(P<0.05)。术后3 h、1 d、3 d,观察组患者的MMSE评分分别为(25.84±3.92)、(27.31±2.18)、(28.16±1.55)分,均高于对照组的(22.91±4.77)、(25.19±4.43)、(26.91±2.99)分(P<0.05)。术后3 h、1d、3 d,观察组的MoCA评分分别为(25.78±3.87)、(27.09±1.97)、(27.78±1.72)分,均高于对照组的(22.41±4.49)、(24.75±4.44)、(26.41±2.75)分(P<0.05)。术毕,观察组的BDNF(3.54±1.22)ng/ml高于对照组的(2.91±1.01)ng/ml,S100β(4.43±0.49)ng/ml低于对照组的(5.35±1.04)ng/ml(P<0.05)。结论电针神庭、百会穴可促进老年腹腔镜胆囊切除术患者术后早期认知功能的恢复,减少术后认知功能障碍的发生。Objective To explore the influence of electroacupuncture at Shenting and Baihui acupoints on early cognitive function of elderly patients after laparoscopic cholecystectomy.Methods 64 elderly patients undergoing laparoscopic cholecystectomy were divided into a control group and an observation group according to a random number table,each consisting of 32 patients.Patients in both groups received conventional anesthesia induction,on this basis,the control group received combined intravenous-inhalation general anesthesia,and the observation group received electroacupuncture at Shenting and Baihui acupoints on the basis of the control group.Comparisons were made between the two groups of patients on the incidence of early postoperative cognitive dysfunction,as well as the scores of the Mini Mental State Examination(MMSE),Montreal Cognitive Assessment Scale(MoCA)at different time points,and cognitive function-related blood indexes[brain-derived neurotrophic factor(BDNF),and central nerve specific protein(S100-β)]before surgery and at the end of surgery.Results The incidence of cognitive dysfunction at 3 h,1 d and 3 d after surgery in the observation group were 34.4%,18.8%and 6.3%,which were lower than 59.4%,43.8%and 25.0%in the control group(P<0.05).At 3 h,1 d and 3 d after surgery,MMSE scores of the observation group were(25.84±3.92),(27.31±2.18)and(28.16±1.55)points,which were higher than(22.91±4.77),(25.19±4.43)and(26.91±2.99)points of the control group(P<0.05).At 3 h,1d and 3 d after surgery,MoCA scores of the observation group were(25.78±3.87),(27.09±1.97)and(27.78±1.72)points,which were higher than(22.41±4.49),(24.75±4.44)and(26.41±2.75)points of the control group(P<0.05).At the end of surgery,the observation group had higher BDNF of(3.54±1.22)ng/ml than(2.91±1.01)ng/ml in the control group,and lower S100βof(4.43±0.49)ng/ml than(5.35±1.04)ng/ml in the control group(P<0.05).Conclusion Electroacupuncture at Shenting and Baihui acupoints can promote the recovery of early cognitive function in eld

关 键 词：电针 神庭穴 百会穴 老年 腹腔镜胆囊切除术 早期认知功能 

分 类 号：R246.2[医药卫生—针灸推拿学]