SIMPLE药学服务模式在哮喘-慢性阻塞性肺疾病重叠综合征患者慢病管理中的应用  

Application of SIMPLE pharmaceutical care model in chronic disease management of patients with asthma-COPD overlap syndrome

作　　者：张峰[1] 姚辉龙 ZHANG Feng;YAO Huilong(Department of the Emergency Pharmacy,Peixian People's Hospital,Xuzhou 221600,China;不详)

机构地区：[1]沛县人民医院急诊药房,江苏徐州221600 [2]沛县人民医院急诊内科,江苏徐州221600

出　　处：《中国处方药》2025年第4期19-22,共4页Journal of China Prescription Drug

摘　　要：目的探讨采用SIMPLE药学服务模式下慢病管理模式对哮喘-慢性阻塞性肺疾病重叠综合征(ACOS)患者进行干预的效果。方法回顾性分析2023年9月~2024年3月期间因患ACOS由某院收治的96例患者的临床资料,将2023年9月~12月入院的ACOS患者作为对照组(n=46),对其采用常规用药指导;将2024年1月~3月入院的ACOS患者作为研究组(n=50),在对照组相同干预方式上应用SIMPLE药学服务模式的慢病管理进行干预。观察两组干预后1个月及3个月时的疾病急性发作或加重的发生情况,比较两组患者干预前后的口服用药依从性与吸入药物使用依从性[Morisky量表(MMAS-8)、中文版吸入药物依从性测试(TAI)]、哮喘控制情况[哮喘控制测试问卷(ACT)]与慢性阻塞性肺疾病(COPD)控制情况[慢性阻塞性肺疾病问卷(CAT)]差异,观察两组患者干预后的安全规范用药情况及干预后3个月内的用药不良反应发生情况。结果研究组在干预后1个月及3个月内的ACOS急性发作或加重率均较对照组更低(P<0.05);干预前,两组口服用药与吸入药物使用的MMAS-8、TAI评分及ACT、CAT评分比较差异无统计学意义(P>0.05),干预后,两组MMAS-8、TAI评分及ACT、CAT评分较干预前均有所升高,且研究组高于对照组(P<0.05);研究组在干预后的各项安全规范用药评分高于对照组,研究组在干预后3个月的用药不良反应总发生率(12.00%)低于对照组(32.61%)(P<0.05)。结论对ACOS患者采用SIMPLE药学服务模式下慢病管理,不仅有助于患者的疾病控制,还能提高其用药依从性与安全规范用药意识,预防用药不良反应发生。Objective To explore the effect of intervention with chronic disease management model under SIMPLE pharmaceutical care model on patients with asthma-COPD overlap syndrome(ACOS).Methods The clinical data of 96 patients with ACOS in a hospital were retrospectively analyzed from September 2023 to March 2024.ACOS patients admitted from September to December,2023 were classified as the control group(n=46),given routine medication guidance.ACOS patients admitted to the hospital from January to March,2024 were included in the study group(n=50),received chronic disease management intervention under SIMPLE pharmaceutical service based on the same intervention model in the control group.The occurrence of acute attack or aggravation of disease was observed at 1 month and 3 months after intervention in the two groups.The differences in oral medication compliance and inhalation medication use compliance[8-item Morisky Medication Adherence Scale(MMAS-8),Test of Adherence to Inhalers(TAI)],asthma control[Asthma Control Test(ACT)]and chronic obstructive pulmonary disease(COPD)control[COPD Assessment Test(CAT)]were compared between groups before and after intervention.The safe and standardized medication use after intervention and occurrence of adverse medication reactions within 3 months after intervention were observed.Results The acute attack or aggravation rates of ACOS in the study group within 1 month and 3 months after intervention were lower than those in the control group(P<0.05).Before intervention,there were no significant differences in MMAS-8 score,TAI score,ACT score and CAT score between the two groups(P>0.05).After intervention,MMAS-8 score,TAI score,ACT score and CAT score in the two groups were risen compared with those before intervention,and the above scores in the study group were higher than those in the control group(P<0.05).The scores of items of safe and standardized medication use in the study group after intervention were higher compared to those in the control group,and the total incidence rate of adve

关 键 词：哮喘-慢性阻塞性肺疾病重叠综合征 SIMPLE药学服务模式 慢病管理 用药依从性 

分 类 号：R563.9[医药卫生—呼吸系统] R562.25[医药卫生—内科学]