Unraveling the complex interactions between plasmonic Ag nanoparticles and biomolecules for enhancing molecular chirality  

作　　者：Chen Wang Yunlong Tao Qingqing Cheng Dandan Lu Chuang Liu Guizeng Yang Xuehao Sun Lichao Sun Qingfeng Zhang 

机构地区：[1]College of Chemistry and Molecular Sciences,Hubei Key Laboratory of Electrochemical Power Sources,Wuhan University,Wuhan 430072,China [2]Suzhou Institute of Wuhan University,Suzhou 215123,China

出　　处：《Science China Chemistry》2025年第2期543-551,共9页中国科学(化学英文版)

基　　金：supported by the National Natural Science Foundation of China(22174104 to Q.Z.);support of the Natural Science Foundation of Jiangsu Province(BK20240448)。

摘　　要：Plasmonic nanostructures have been widely employed to enhance the chiral light-matter interactions for chirality sensing owing to their intriguing optical properties.However,a quantitative understanding of the correlation between enhanced molecular chirality and plasmonic properties in plasmonic nanoparticle-molecule complexes remains a challenge yet to be addressed.Here we demonstrate the complex interactions between Ag nanoparticles and biomolecules that generate distinct plasmonic circular dichroism signals ranging from UV to visible wavelengths.By deliberately changing the surface coverage of chiral molecules,the geometry of Ag nanoparticles,and the aggregation states of the complexes,three distinct underlying mechanisms were found to be intertwined and hybridized for enhancing circular dichroism signals.We further employed the chiral plasmonic nanoparticle-molecule complexes to quantify the enantiomeric purity of cysteine and explore their possible applications in other chiral molecules.The insights gained from this work shed light on the underlying mechanisms dictating the enhanced circular dichroism signals of chiral plasmonic nanoparticle-molecule complexes.

关 键 词：chiral plasmonics plasmonic circular dichroism nanoparticle-molecule complexes Ag nanoparticles chirality sensing 

分 类 号：O62[理学—有机化学]