A novel arterial coupler with non-return snap-fit connection approach optimized arterial end-to-end anastomotic technique:An experimental study  

作　　者：Hong-Bo Guo Mo-Fei Wang Ren-Qi Yin Kang-Kang Zhi 

机构地区：[1]Department of Vascular and Endovascular Surgery,Changzheng Hospital,Naval Medical University,Shanghai,200003,China [2]School of Health Science and Engineering,University of Shanghai for Science and Technology,Shanghai,200093,China

出　　处：《Chinese Journal of Traumatology》2025年第1期13-21,共9页中华创伤杂志(英文版)

基　　金：supported by the innovative clinical research project of the Second Affiliated Hospital of Naval Military Medical University(2020YLCYJ-Y17);the third batch of medical engineering cross projects of Naval Military Medical University(10-21-308-415);the National Natural Science Foundation of China(No.81971710);the Biomedical Science and Technology Supporting Special Project,Shanghai Science and Technology Innovation Action Plan(2020)(No.20S31902000).

摘　　要：Purpose:Hand-sewn anastomosis as the gold standard of vascular anastomosis cannot fully meet the requirements of vascular anastomosis in speed and quality.Various vascular couplers have been developed to ameliorate this situation.Most of them are mainly used for venous anastomosis rather than arterial anastomosis.Although it is generally acknowledged that in almost all operations involving vascular reconstruction,it is the arteries that need to be anastomosed faster and more accurately and not the veins.A dedicated device is needed for creating arterial anastomosis in an easy,timesaving,less damaging but reliable procedure.Therefore,we plan to develop a novel arterial coupler device and test pre-clinical safety and effectiveness.Methods:In this cohort study,the rationality of this novel arterial coupler was preliminarily tested by finite element analysis before it was manufactured.Several factors restrict the use of vascular couplers in arterial anastomosis,such as arterial eversion,fixation,etc.The manufactured arterial couplers underwent in vitro and in vivo experiments.In vitro,isolated arteries of beagles were anastomosed with the assistance of an arterial coupler,and the anastomosed arteries were evaluated through anti-traction tests.In animal experiments,the bilateral femoral arteries of 5 beagles served as a control group.After dissection,the femoral artery on one side was randomly selected to be anastomosed with a quick arterial coupler(QAC)(QAC group),and the femoral artery on the other side was anastomosed by the same person using an end-to-end suture technique with a 6-0 Prolene suture(suture group).The bilateral femoral arteries of 5 beagles were used for coupler-assisted anastomosis and hand-sewn anastomosis in vivo,respectively.Success rate,blood loss,anastomotic time,clamp time,total operation time,and patency rate were recorded.The patency of anastomosed arteries was assessed using vascular Doppler ultrasound,electromagnetic flowmeter,and pathological examination(6 weeks after surgery).Results:As

关 键 词：COUPLER Vascular anastomosis Arterial anastomosis END-TO-END Novel device 

分 类 号：R654.3[医药卫生—外科学]