OsbZIP27 coordinates with OsHUB1 and OsHUB2 to modulate drought tolerance in rice  

作　　者：Zuntao Xu Yachun Yang Fei Zhang Hao Li Hui Ma Wenge Wu Yong Ding 

机构地区：[1]Anhui Province Key Laboratory of Rice Genetics and Breeding,Rice Research Institute,Anhui Academy of Agricultural Sciences,Hefei,Anhui 230031,China [2]Biological Breeding Laboratory of Anhui Province,Hefei,Anhui 230031,China [3]Ministry of Education Key Laboratory for Membraneless Organelles and Cellular Dynamics,Hefei,Anhui 230027,China [4]School of Life Sciences,University of Science and Technology of China,Hefei,Anhui 230027,China [5]The Grain Industry Research Institute of Anhui Agricultural University,Hefei,Anhui 230036,China

出　　处：《Journal of Genetics and Genomics》2025年第2期168-178,共11页遗传学报(英文版)

基　　金：supported by the Open Research Fund Program of Anhui Province Key Laboratory of Rice Genetics and Breeding(SDKF-2023-02);the Postdoctoral Research Program of Anhui Province(2022B603);the Key Research and Development Projects in Anhui Province(2023n06020035);the National Natural Science Foundation of China(32230017,U19A2021,and 32321001);the Natural Science Foundation of Anhui province(2408085MC083);the Global Select Project(DJK-LX-2022007)of the Institute of Health and Medicine;the Hefei Comprehensive National Science Center,the Fundamental Research Funds for the Central Universities(WK9100000047);the Anhui Academy of Agricultural Sciences Young Talent Program(QNYC-201902).

摘　　要：Histone H2B ubiquitination(H2Bub)is positively linked to transcriptional activation,but the genetic programs affected by H2Bub to enhance drought tolerance remain largely unknown.Here,we show that OsbZIP27 interacts directly with OsHUB1/2 to regulate drought tolerance in rice by binding to the promoters of OsHAK1 and OsGLN1 to achieve H2Bub and transcriptional activation.Consistently,mutations in OsbZIP27 reduce transcription of OsHAK1 and OsGLN1,resulting in increased sensitivity to drought stress.Moreover,loss of OsHUB1 and OsHUB2 function causes hypersensitivity to drought stress,whereas OsHUB2 overexpression enhances drought tolerance.Together,our results indicate that OsbZIP27 coordinates with OsHUB1/2 to enhance rice drought tolerance by increasing H2Bub and expression of OsHAK1 and OsGLN1.

关 键 词：H2B monoubiquitination Drought stress bZIP transcription factor Ring domain protein Potassium transporter GLUCANASE 

分 类 号：S511[农业科学—作物学]