复方斯亚旦生发酊治疗女性雄激素性脱发的临床疗效观察  

Clinical observation on the therapeutic effect of compound siyadan hair growth tincture in the treatment of female androgenic alopecia

作　　者：阿彩岭 田茜 田波 孟祖东 E Cailing;TIAN Xi;TIAN Bo;MENG Zudong(Department of Dermatology,Renmin Hospital,Hubei University of Medicine,Shiyan 442000,China)

机构地区：[1]十堰市人民医院(湖北医药学院附属人民医院)皮肤科,湖北十堰442000 [2]泰康同济(武汉)医院皮肤科,湖北武汉430050

出　　处：《中国美容整形外科杂志》2025年第1期49-52,I0010,共5页Chinese Journal of Aesthetic and Plastic Surgery

摘　　要：目的评价复方斯亚旦生发酊治疗女性雄激素性脱发(female androgenic alopecia,FAGA)的临床疗效及安全性。方法采用前瞻性随机双盲对照临床研究,纳入自2023年1—12月,十堰市人民医院(湖北医药学院附属人民医院)皮肤科就诊的60例FAGA患者,随机分为对照组(n=30)和研究组(n=30),分别予以5%米诺地尔酊和复方斯亚旦生发酊治疗24周,比较治疗前后毛发镜数据、患者症状评分、治疗总有效率及不良反应等情况。结果毛发镜数据显示,两组患者治疗后毛发生长情况均较治疗前改善,其差异有统计学意义(P<0.05);患者症状评分显示,两组患者治疗后脱发症状较治疗前均有改善(P<0.05);研究组改善情况优于对照组,差异有统计学意义(P<0.05);两组患者治疗总体有效率相当,差异无统计学意义(P>0.05);两组患者不良反应均较轻微,差异无统计学意义(P>0.05)。结论复方斯亚旦生发酊能够有效地治疗FAGA,远期疗效和安全性较好,值得临床进一步深入研究。Objective To evaluate the clinical efficacy and safety of compound siyadan hair growth tincture in the treatment of female androgenic alopecia(FAGA).Methods A prospective randomized double-blind controlled clinical study design was adopted.From January to December 2023,a total of 60 FAGA patients were included.They were randomly divided into a control group(n=30)and a study group(n=30),and treated with 5%minoxidil tincture and compound siyadan hair growth tincture for 24 weeks,respectively.The dermoscopy data,symptom scores,total effective rate of treatment,and adverse reactions before and after treatment were compared.Results The hair growth of both groups of patients improved after treatment compared to before,and the difference was statistically significant(P<0.05).The hair loss symptoms of two groups of patients improved after treatment compared to before treatment(P<0.05),the difference between the two groups of patients was statistically significant(P<0.05),and the improvement in the study group was better than that in the control group.The overall effective rates of the two groups of patients were comparable,with no statistically significant difference(P>0.05).Both groups of patients had mild adverse reactions,and the difference was not statistically significant(P>0.05).Conclusion Compound siyadan hair growth tincture can effectively treat female androgenic alopecia,with good long-term efficacy and safety,and is worthy of further clinical research.

关 键 词：女性雄激素性脱发 复方斯亚旦生发酊 米诺地尔 疗效观察 

分 类 号：R73[医药卫生—肿瘤]