混合痔患者外剥内扎术后苦参汤熏洗对术后疼痛与促炎因子的影响  

Effect of Kushen Decoction Fumigation on Postoperative Pain and Proinflammatory Factors in Patients with Mixed Hemorrhoids after External Stripping and Internal Ligation

作　　者：石建敏 邹秋红 邹丹丹 SHI Jianmin;ZOU Qiuhong;ZOU Dandan(Surgery Department,Leping Hospital of Traditional Chinese Medicine,Leping 333300,China)

机构地区：[1]乐平市中医医院外科,江西乐平333300

出　　处：《中国医学创新》2025年第4期94-97,共4页Medical Innovation of China

摘　　要：目的:探究苦参汤熏洗对混合痔患者外剥内扎术后疼痛与促炎因子的影响。方法:前瞻性选取90例2021年6月—2024年4月在乐平市中医医院接受外剥内扎术治疗的混合痔患者,随机分为常规组和试验组,各45例,常规组给予高锰酸钾溶液熏洗,试验组给予苦参汤熏洗,均治疗2周。比较两组的临床疗效、症状改善时间、肛门功能及促炎因子[白介素-1(IL-1)、白介素-6(IL-6)及肿瘤坏死因子-α(TNF-α)]水平,并比较两组治疗第3、7、14天肛周疼痛评分。结果:试验组的治疗总有效率高于常规组(P<0.05);治疗后,试验组的创面愈合时间、坠胀感消失时间、疼痛消失时间、止血时间均短于常规组(P<0.05);治疗后试验组肛管舒张压、静息压、最大收缩压均较常规组高,肛管高压带长度较常规组短(P<0.05);治疗后试验组TNF-α、IL-1、IL-6水平均低于常规组(P<0.05),治疗第3、7、14天,试验组肛周疼痛评分均低于常规组(P<0.05)。结论:混合痔患者外剥内扎术后进行苦参汤熏洗疗效良好,能显著缓解肛周疼痛,降低炎症反应,缩短症状改善时间,改善肛门功能。Objective:To explore the effect of Kushen Decoction fumigation on pain and proinflammatory factors in patients with mixed hemorrhoids after external stripping and internal ligation.Method:A total of 90 patients with mixed hemorrhoids who received external stripping and internal ligation in Leping Hospital of Traditional Chinese Medicine from June 2021 to April 2024 were prospectively selected and randomly divided into conventional group and experimental group,with 45 cases in each group.The conventional group was given potassium permangate solution fumigation,and the experimental group was given Kushen Decoction fumigation,and both groups were treated for 2 weeks.The clinical efficacy,symptom improvement time,anal function and proinflammatory factors[interleukin-1(IL-1),interleukin-6(IL-6)and tumor necrosis factor-α(TNF-α)]levels were compared between the two groups,and the perianal pain scores of the two groups were compared at the 3rd,7th and 14th day of treatment.Result:The total effective rate of experimental group was higher than that of conventional group(P<0.05).After treatment,the wound healing time,the disappearance time of tumescence,the disappearance time of pain and the hemostasis time of experimental group were shorter than those of conventional group(P<0.05).After treatment,the diastolic pressure,resting pressure and maximum systolic pressure of anal canal in experimental group were higher than those in conventional group,and the length of anal canal high pressure band was shorter than that in conventional group(P<0.05).After treatment,the levels of TNF-α,IL-1 and IL-6 in experimental groups were lower than those in conventional group(P<0.05),and perianal pain scores in experimental groups were lower than those in conventional group at the 3rd,7th and 14th day of treatment(P<0.05).Conclusion:The effect of Kushen Decoction fumigation on mixed hemorrhoid patients after external stripping and internal ligation is good,which can significantly relieve perianal pain,reduce inflammatory response,shorten

关 键 词：苦参汤熏洗 混合痔 外剥内扎术 术后疼痛 促炎因子 

分 类 号：R266[医药卫生—中医外科学]