柴胡疏肝散加减治疗肝胃不和型功能性消化不良的效果及对胃功能的影响  

Effect of Modified Chaihu Shugan Powder on Incoordination between Liver and Stomach Type Functional Dyspepsia and Its Influence on Gastric Function

作　　者：方洋 FANG Yang(Department of Gastroenterology,Macheng Hospital of Traditional Chinese Medicine,Macheng 438300,China)

机构地区：[1]麻城市中医医院消化内科,湖北麻城438300

出　　处：《中国医学创新》2025年第4期102-106,共5页Medical Innovation of China

摘　　要：目的:分析柴胡疏肝散加减治疗肝胃不和型功能性消化不良(FD)的效果及对胃功能的影响。方法:选取2021年3月—2024年2月在麻城市中医医院接受治疗的80例肝胃不和型FD患者作为研究对象,通过随机数字表法分为两组,对照组(n=40,接受常规西药治疗)和研究组(n=40,在对照组基础上接受柴胡疏肝散加减治疗)。观察并比较两组中医症候积分及胃功能指标,评估两组临床治疗效果,并对不良反应发生情况进行记录。结果:研究组总有效率高于对照组(92.50%vs 75.00%),差异有统计学意义(P<0.05);相较治疗前,两组治疗后各中医症候积分及总积分均降低,且研究组均低于对照组,差异均有统计学意义(P<0.05);两组治疗后胃泌素(GAS)和胃动素(MTL)水平均明显较治疗前升高,且研究组均较对照组高,差异均有统计学意义(P<0.05);研究组不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论:在肝胃不和型FD患者中应用柴胡疏肝散加减治疗有显著的临床效果,不仅能有效缓解患者的临床症状,还能改善胃功能,且有良好的安全性。Objective:To analyze the effect of modified Chaihu Shugan Powder on incoordination between liver and stomach type functional dyspepsia(FD)and its influence on gastric function.Method:A total of 80 patients with incoordination between liver and stomach type FD who received treatment in Macheng Hospital of Traditional Chinese Medicine from March 2021 to February 2024 were selected as the study objects and divided into two groups by random number table method.The control group(n=40,received conventional western medicine treatment)and the study group(n=40,received modified Chaihu Shugan Powder treatment on the basis of control group).The TCM syndromes scores and gastric function index of the two groups were observed and compared,the clinical therapeutic effect of the two groups were evaluated,and the occurrence of adverse reactions were recorded.Result:The total effective rate of the study group was higher than that of the control group(92.50%vs 75.00%),the difference was statistically significant(P<0.05).Compared with before treatment,TCM syndromes scores and total scores of both groups after treatment were decreased,and those in the study group were lower than those in the control group,the differences were statistically significant(P<0.05).The levels of gastrin(GAS)and motilin(MTL)in both groups after treatment were significantly higher than those before treatment,and those in the study group were higher than those in the control group,the differences were statistically significant(P<0.05).The incidence of adverse reactions in the study group was lower than that in the control group,the difference was statistically significant(P<0.05).Conclusion:The application of modified Chaihu Shugan Powder in the treatment of patients with incoordination between liver and stomach type FD has significant clinical effect,which can not only effectively alleviate the clinical symptoms of patients,but also improve the gastric function,and has good safety.

关 键 词：柴胡疏肝散加减 功能性消化不良 肝胃不和型 胃功能 

分 类 号：R259[医药卫生—中西医结合]