2型糖尿病周围神经病变患者足底动静态压力参数比较及相关因素分析  

Comparison of plantar dynamic and static pressure parameters in patients with type 2 diabetes mellitus combined with diabetic peripheral neuropathy and analysis of related factors

作　　者：王静[1] 王晖 苗宇宽 倪英群[1] WANG Jing;WANG Hui;MIAO Yukuan;NI Yingqun(Department of Endocrinology,the First Affiliated Hospital of Anhui University of Chinese Medicine,Hefei 230031,Anhui,China;不详)

机构地区：[1]安徽中医药大学第一附属医院内分泌科,安徽合肥230031 [2]安徽中医药大学护理学院,安徽合肥230038

出　　处：《实用医学杂志》2025年第4期522-528,共7页The Journal of Practical Medicine

基　　金：国家自然科学基金项目(编号:82274468);安徽省高等学校省级质量工程项目(编号:2022xskc056);安徽中医药大学科研基金项目(编号:2021yfylc55)。

摘　　要：目的比较2型糖尿病(T2DM)患者与合并糖尿病周围神经病变(DPN)患者足底动态和静态压力参数,并分析相关因素。方法回顾性选取单纯T2DM组47例及T2DM合并DPN组57例。记录两组足底动静态压力参数及相关临床资料。结果合并DPN组年龄、体质量指数(BMI)、胆固醇、甘油三酯显著高于单纯T2DM组(P<0.05)。合并DPN组左右足平均压强、左足部轴角、左足前足负荷比、后足负荷比、负荷比内侧及外侧均大于单纯T2DM组,差异有统计学意义(P<0.05)。患者足底动静态最大压强、平均压强、足底受压总面积均与BMI、甘油三酯呈显著正相关。多元线性回归分析示,动态压力左足足部轴角大小与甘油三酯水平有关(P<0.05);左足前后负荷比与糖尿病病程有关(P<0.05);静态压力中双足面积、最大压强、平均压强均与BMI有关。结论合并DPN组动态足底压力平均压强和左足轴角、负荷比相较单纯T2DM组对足部功能更有影响;且无论是否合并DPN,均需重视患者的足底压力测定;及早干预与足底动静态压力相关联指标如BMI、甘油三酯,为预防糖尿病足发生提供临床参考。Objective To compare plantar dynamic and static pressure parameters between patients with type 2 diabetes mellitus(T2DM)and those with combined diabetic peripheral neuropathy(DPN),and to analyze associated factors.Methods A retrospective analysis was conducted on 47 cases in the pure T2DM group and 57 cases in the T2DM combined with DPN group.The plantar dynamic and static pressure parameters,along with relevant clinical data,were recorded for each group.Results Age,BMI,cholesterol,and triglycerides were significantly higher in the combined DPN group compared to the T2DM group(P<0.05).The average pressure on both feet and the axial angle of the left foot were also significantly greater in the combined DPN group than in the simple T2DM group(P<0.05).A larger axial angle suggests an impact on gait or foot function.Additionally,the forefoot loading ratio,hindfoot loading ratio,and medial⁃lateral loading ratio of the left foot were all significantly higher in the combined DPN group compared to the simple T2DM group(P<0.05).For static pressure parameters,no statistically significant differences were observed between the two groups in terms of foot area,load,maximum pressure,or average pressure(P>0.05).Spearman′s univariate analysis revealed that plantar dynamic and static maximum pressure,mean pressure,and total plantar pressure area were significantly and positively correlated with BMI and triglycerides.Multiple linear regression analysis indicated that the axial angle of the left foot during dynamic pressure was associated with triglyceride levels(P<0.05),the load ratio of the left anterior and posterior foot was related to the duration of diabetes mellitus(P<0.05),and the bipedal area,maximal pressure,and mean pressure during static pressure were all associated with BMI.Conclusions Dynamic plantar pressure mean compression,left foot axis angle,and loading ratio had a greater influence on foot function in the combined DPN group compared to the T2DM group alone.Regardless of the presence of DPN,attention should b

关 键 词：2型糖尿病 周围神经病变 足底动态压力 足底静态压力 相关因素 

分 类 号：R587.1[医药卫生—内分泌]