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作 者:黎建琴 董桂生 LI Jianqin;DONG Guisheng(Department of Obstetrics and Gynecology,Fuzhou Maternal and Child Health Hospital,Fuzhou 344000,China;不详)
机构地区:[1]抚州市妇幼保健院(抚州市第二人民医院)妇产科,江西抚州344000
出 处:《中国医学创新》2025年第5期48-51,共4页Medical Innovation of China
基 金:抚州市指导性科技计划项目(抚科社字【2023】7号序号37)。
摘 要:目的:探究滋肾育胎丸联合常规西药治疗多囊卵巢综合征(PCOS)的效果。方法:选取2022年5月-2024年8月抚州市妇幼保健院收治的102例PCOS患者作为研究对象,按信封抽签法随机分为常规组(n=51)和联合组(n=51)。常规组给予常规西药治疗,联合组给予滋肾育胎丸联合常规西药治疗,比较两组的临床疗效、性激素水平、卵巢体积、子宫内膜厚度及不良反应发生情况。结果:联合组总有效率高于常规组,差异有统计学意义(P<0.05);治疗后,联合组卵泡刺激素(FSH)、黄体生成素(LH)、雌二醇(E2)、睾酮(T)均低于常规组,差异均有统计学意义(P<0.05);治疗后,联合组子宫内膜厚度高于常规组,卵巢体积小于常规组,差异均有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:滋肾育胎丸联合常规西药治疗PCOS患者,可显著提高治疗效果,改善性激素水平、卵巢体积和子宫内膜厚度,且安全性较高。Objective:To explore the effect of Zishen Yutai Pills combined with conventional western medicine on polycystic ovary syndrome(PCOS).Method:A total of 102 patients with PCOS admitted to Fuzhou Maternal and Child Health Hospital from May 2022 to August 2024 were selected as the study objects,and they were randomly divided into conventional group(n=51)and combined group(n=51)according to envelope drawing method.The conventional group was treated with conventional western medicine,and the combined group was treated with Zishen Yutai Pills combined with conventional western medicine.The clinical efficacy,sex hormone levels,ovarian volume,endometrial thickness and the occurrence of adverse reactions were compared between the two groups.Result:The total effective rate of the combined group was higher than that of the conventional group,the difference was statistically significant(P<0.05).After treatment,follicle stimulating hormone(FSH),luteinizing hormone(LH),estradiol(E2)and testosterone(T)in combined group were lower than those in conventional group,the differences were statistically significant(P<0.05).After treatment,the endometrial thickness of combined group was higher than that of conventional group,and the ovarian volume was lower than that of conventional group,the differences were statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Zishen Yutai Pills combined with conventional western medicine in the treatment of PCOS patients can significantly improve the therapeutic effect,improve the level of sex hormones,ovarian volume and endometrial thickness,and have high safety.
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