Urinary tract infections in kidney transplant patients admitted to hospital:A real-life experience  

作　　者：Biagio Pinchera Rosa Carrano Elisa Schettino Alessia D'Agostino Emilia Trucillo Federica Cuccurullo Fabrizio Salemi Amerigo Piccione Ivan Gentile 

机构地区：[1]Section of Infectious Diseases,Department of Clinical Medicine and Surgery,University of Naples“Federico II”,Naples 80131,Italy [2]Section of Nephrology,Department of Public Health,University of Naples“Federico II”,Naples 80131,Italy

出　　处：《World Journal of Transplantation》2025年第2期228-236,共9页世界移植杂志(英文)

摘　　要：BACKGROUND Urinary tract infections(UTIs)in kidney transplant patients are a challenge.AIM To evaluate epidemiology,clinical status,therapeutic management,and clinical outcome of kidney transplant patients in a university hospital for UTI.METHODS We conducted a retrospective observational study,enrolling all kidney transplant patients hospitalized for UTI,with the objective to evaluate the epidemiology,clinical status,therapeutic management,and clinical outcome of kidney transplant patients.RESULTS From our real-life experience,infection with multidrug-resistant germs was confirmed as a risk factor for the severe evolution of the infection.At the same time,the re-evaluation of immunosuppressive therapy could be an important therapeutic strategy in the course of infection.CONCLUSION Prompt initiation of empiric antibiotic therapy upon initiation of microbiological investigations may reduce the risk of severe infection progression.

关 键 词：Urinary tract infections Kidney transplant Multidrug-resistant germ Solid organ transplant recipient Empiric therapy 

分 类 号：R699.2[医药卫生—泌尿科学]