Post-reperfusion syndrome in liver transplant recipients:What is new in prevention and management?  

作　　者：Austin James Puchany Ibtesam Hilmi 

机构地区：[1]Department of Anesthesiology&Perioperative Medicine,University of Pittsburgh Medical Center,Pittsburgh,PA 15213,United States [2]School of Medicine,University of Pittsburgh,Pittsburgh,PA 15213,United States [3]Department of Anesthesiology and Perioperative Medicine,Clinical and Translational Science Institute,University of Pittsburgh,School of Medicine,Pittsburgh,PA 15213,United States

出　　处：《World Journal of Critical Care Medicine》2025年第2期65-74,共10页世界重症医学杂志(英文)

摘　　要：Post-reperfusion syndrome(PRS)in liver transplant recipients remains one of the most dreaded complications in liver transplant surgery.PRS can impact the short-term and long-term patient and graft outcomes.The definition of PRS has evolved over the years,from changes in arterial blood pressures and heart and/or de-creases in the systemic vascular resistance and cardiac output to including the fibrinolysis and grading the severity of PRS.However,all that did not reflect on the management of PRS or its impact on the outcomes.In recent years,new scientific techniques and new technology have been in the pipeline to better understand,manage and maybe prevent PRS.These new methods and techniques are still in the infancy,and they have to be proven not in prevention and management of PRS but their effects in the patient and graft outcomes.In this article,we will review the long history of PRS,its definition,etiology,mana-gement and most importantly the new advances in science and technology to prevent and properly manage PRS.

关 键 词：Liver transplant Post-reperfusion syndrome Machine perfusion Hypothermic machine perfusion Normothermic machine perfusion Caval blood flush vent Ischemic pre-conditioning 

分 类 号：R657.3[医药卫生—外科学]