Coronary imaging characteristics and risk factors in patients with type 2 diabetes mellitus with coronary heart disease complication  

作　　者：Chang-Jie Pan Tao Wang Ruo-Han Yin Xiao-Qiang Tang Chun-Hong Hu 

机构地区：[1]Department of Radiology,The First Affiliated Hospital of Soochow University,Suzhou 215006,Jiangsu Province,China [2]Department of Radiology,The Affiliated Changzhou No.2 People’s Hospital of Nanjing Medical University,Changzhou 215006,Jiangsu Province,China

出　　处：《World Journal of Diabetes》2025年第4期96-105,共10页世界糖尿病杂志(英文)

基　　金：Supported by the Science and Technology Major Project of Changzhou Science and Technology Bureau,No.CE20205047;Natural Science Foundation of Xinjiang Uygur Autonomous Region,No.2022D01F52;Changzhou A Major Scientific Research Project of the Municipal Health Commission,No.ZD202220.

摘　　要：BACKGROUND Coronary heart disease(CHD)is a prevalent type 2 diabetes mellitus(T2DM)complication.Further,the risk stratification before angiography may help diagnose T2DM with CHD early.However,few studies have investigated the coronary imaging characteristics and risk factors of patients with T2DM complicated with CHD.AIM To compare the differences in coronary imaging between patients with T2DM with and without CHD,determine the risk factors of T2DM complicated with CHD,and establish a predictive tool for diagnosing CHD in T2DM.METHODS This study retrospectively analyzed 103 patients with T2DM from January 2022 to May 2024.They are categorized based on CHD occurrence into:(1)The control group,consisting of patients with T2DM without CHD;and(2)The observation group,which includes patients with T2MD with CHD.Age,sex,smoking and drinking history,CHD family history,metformin(MET)treatment pre-admission,body mass index,fasting blood glucose(FBG),triglyceride(TG),total cholesterol,high-density lipoprotein cholesterol,low-density lipoprotein cholesterol(LDL-C),serum creatinine,blood urea nitrogen(BUN),alanine aminotransferase,aspartate aminotransferase,glycosylated hemoglobin(HbA1c),and coronary imaging data of both groups were collected from the medical record system.Logistic risk analysis was conducted to screen risk factors.The prediction model’s prediction efficiency was evaluated with receiver operating characteristic curves.RESULTS The control and observation groups consisted of 48 and 55 cases,respectively.The two groups were statistically different in terms of age(t=2.006,P=0.048),FBG(t=6.038,P=0.000),TG(t=2.015,P=0.047),LDL-C(t=2.017,P=0.046),and BUN(t=2.035,P=0.044).The observation group demonstrated lower proportions of patients receiving MET(χ^(2)=5.073,P=0.024)and higher proportions of patients with HbA1c of>7.0%(χ^(2)=6.980,P=0.008)than the control group.The observation group consisted of 15,17,and 23 cases of moderate stenosis,severe stenosis,and occlusion,respectively,with a greater number of coronar

关 键 词：Type 2 diabetes mellitus Coronary heart disease Coronary imaging Risk factors COMPLICATION Risk prediction model 

分 类 号：R587.1[医药卫生—内分泌]