Comprehensive impact of PPARG mutations in familial partial lipodystrophy type 3:Diagnosis,therapeutic strategies  

作　　者：Heng-Li Lai Liu Yang 

机构地区：[1]Department of Cardiology,Jiangxi Provincial People's Hospital,The First Affiliated Hospital of Nanchang Medical College,Nanchang 330006,Jiangxi Province,China

出　　处：《World Journal of Diabetes》2025年第4期310-313,共4页世界糖尿病杂志(英文)

摘　　要：This article reviews a paper in the World Journal of Diabetes.The study uncovers the link between PPARG gene mutations and metabolic disorders,such as insulin resistance,diabetes,and hypertriglyceridemia,and emphasizes the crucial role of genetic testing in precise diagnosis and personalized treatment.This article further points out that in-depth investigation into the clinical heterogeneity of PPARG mutations and their underlying mechanisms can contribute to optimizing management strategies.Meanwhile,the development of more effective targeted therapies and the conduct of extensive genomic research are of great significance for understanding familial partial lipodystrophy type 3 and related metabolic syndromes.

关 键 词：Familial partial lipodystrophy type 3 Genetic testing Metabolic disorders Personalized treatment 

分 类 号：R587.1[医药卫生—内分泌]