连续性肾脏替代治疗中的血流速度:现状与展望  

Blood flow rate in continuous renal replacement therapy:current research status and future prospect

作　　者：杨滨瑜 刘彩虹 赵宇亮[2] YANG Binyu;LIU Caihong;ZHAO Yuliang(West China School of Clinical Medicine,Sichuan University,Chengdu Sichuan 610041;Department of Nephrology,West China Hospital,Sichuan University,Chengdu Sichuan 610041,China)

机构地区：[1]四川大学华西临床医学院,四川成都610041 [2]四川大学华西医院肾脏内科,四川成都610041

出　　处：《实用心电与临床诊疗》2025年第1期136-142,共7页PRACTICAL ELECTROCARDIOLOGY AND CLINICAL TREATMENT

基　　金：国家重点研发计划项目(2023YFC2411800);四川大学华西医院1·3·5基金临床研究孵化项目(2020HXFH014)。

摘　　要：连续性肾脏替代治疗(continuous renal replacement therapy,CRRT)是一种用于急性肾损伤等危重症患者的体外血液净化方法,其治疗效果受到体外循环血流速度的影响。低血流速度与CRRT回路凝血、治疗中断显著相关,而血流速度过快则可能导致回路压力过高,同样会影响治疗效果。目前CRRT最佳回路血流速度仍未明确,且治疗应考虑到不同人群的需求;如何设置不同治疗场景下的血流速度仍是亟待解决的问题。本文针对CRRT中血流速度的研究现状和展望进行综述,旨在为临床实践和后续研究提供参考。Continuous renal replacement therapy(CRRT)is an extracorporeal blood purification method used for critically ill patients with conditions such as acute kidney injury.The therapeutic effect of CRRT is influenced by the blood flow rate in the extracorporeal circuit.Low blood flow rate is significantly associated with circuit clotting and treatment interruption,while excessively high blood flow rate may lead to elevated circuit pressure,similarly impair therapeutic outcomes.At present,the optimal extracorporeal blood flow rate for CRRT remains unclear.Additionally,the special needs of different populations should be considered during the treatment,and how to set blood flow rate in various treatment scenarios is still an unresolved issue.This article provides a review of the current research status and future prospect of blood flow rate in CRRT,aiming to offer references for clinical practice and further research in this area.

关 键 词：连续性肾脏替代治疗 血流速度 凝血 溶质清除 

分 类 号：R692[医药卫生—泌尿科学]