中药英路黄金宝对断奶仔猪生长性能、腹泻率及肠道微生物的影响  

Effects of Yinglu Huangjinbao on growth performance, diarrhea rate and fecal microbiota of weaned piglets

作　　者：程宁 张铖 向红琳 杨程 苏柘僮 孙英峰 Cheng Ning;Zhang Cheng;Xiang Honglin;Yang Cheng;Su Zhetong;Sun Yingfeng(Tianjin Key Laboratory of Agricultural Animal Breeding and Healthy Husbandry,College of Animal Science and Veterinary Medicine,Tianjin Agricultural University,Tianjin 300392,China;Chengdu Xinhai Yinglu Biomedical Technology Co.,Ltd.,Chengdu 611633,China)

机构地区：[1]天津农学院动物科学与动物医学学院天津市农业动物繁育与健康养殖重点实验室,天津300392 [2]成都馨海英路生物医药科技有限公司,成都611633

出　　处：《天津农学院学报》2025年第1期30-33,共4页Journal of Tianjin Agricultural University

基　　金：企业横向委托项目(20220607);天津市重点研发计划科技支撑重点项目(22YFZCSN00100)。

摘　　要：旨在研究中药英路黄金宝(杜仲叶提取物)对断奶仔猪生长性能、腹泻率及肠道微生物的影响,将40头26±2日龄的“杜长大”三元断奶仔猪随机分为4组:基础日粮对照组,基础日粮+0.2 g/kg BW(体重)中药组,基础日粮+0.4 g/kg BW中药组,基础日粮+0.8 g/kg BW中药组,饲喂周期共14 d,对其日增重、腹泻率、肠道微生物群落及血清免疫指标进行检测。结果表明,与对照组相比,高中低剂量组均可提高断奶仔猪平均日增重(ADG)和平均日采食量(ADFI),降低料重比(F/G)(P<0.05),且低剂量组(0.2 g/kg BW)的断奶仔猪F/G降低了21.72%、ADFI提高了12.21%,并使断奶仔猪腹泻率降低了26.20%;Alpha多样性分析显示,ACE、Chao 1和shannon指数显著提高,simpson指数显著降低(P<0.05),提示断奶仔猪肠道微生物群落多样性丰富了;仔猪血清中抗氧化应激指标T-AOC、T-SOD、GSH-Px显著提高,MDA活性显著降低(P<0.01)。中药英路黄金宝能够有效提高断奶仔猪平均日增重,降低断奶仔猪料重比和腹泻率,有助于提高断奶仔猪抗氧化应激力,丰富仔断奶猪肠道微生物菌群。In order to study the effects of Yinglu Huangjinbao(Eucommia ulmoides leaf extract)on the growth performance,diarrhea rate and fecal microbiota of weaned piglets,40 piglets at the age of 26±2 days were selected and randomly divided into four groups.Group 1 was basic diet control group,groups 2 to 4 were traditional Chinese medicine feeding groups,and 0.2 g/kg,0.4 g/kg and 0.8 g/kg Huangjinbao feed additives were added to the basal diet according to body weight,respectively.The test period was 14 days,the daily weight gain,diarrhea rate,intestinal microbiota,and serum immune indicators were tested.The results showed that,compared with the control group,the Yinglu Huangjinbao could increase the average daily gain(ADG)and average daily feed intake(ADFI)of weaned piglets,as well as reduce the feed to weight ratio(F/G)(P<0.05)in the high,medium,and low dose groups.In addition,the F/G was reduced by 21.72%and the ADFI was increased by 12.21%in the low dose(0.2 g/kg BW)of weaned piglets,and the diarrhea rate was also reduced by 26.20%.Alpha diversity analysis showed ACE,Chao 1,and Shannon index were significantly increased and Simpson index was decreased in the test groups(P<0.05),indicating an enrichment of gut microbiota diversity in weaned piglets.The antioxidant stress indicators of T-AOC,T-SOD,GSH-Px in piglet serum were significantly increased and MDA activity was significantly reduced(P<0.01).Huangjinbao could effectively increase the average daily weight gain,reduce the feed to weight ratio and diarrhea rate,improve the antioxidant stress capacity and enrich the gut microbiota of weaned piglets.

关 键 词：中药 英路黄金宝 断奶仔猪 生长性能 腹泻率 

分 类 号：S859.3[农业科学—临床兽医学]